The Detroit Tigers host the San Francisco Giants on on May 28, 2025. First pitch from Comerica Park is scheduled for 1:10 p.m. ET; the game will be broadcast on FDSDET.
Find my MLB betting preview and Giants vs Tigers prediction below, as well as probable pitchers, betting trends, injury reports and more.
Giants vs Tigers Prediction
- Giants vs Tigers picks: Giants ML -105
My Giants vs Tigers best bet is on Giants moneyline. Make sure to find the best odds by checking our live MLB odds page.
Giants vs Tigers Odds
| Giants Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +155 | 8 -105o / -115u | -105 |
| Tigers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -185 | 8 -105o / -115u | -115 |
Giants vs Tigers Projected Starting Pitchers
| Landen Roupp (SF) | Stat | Jackson Jobe (DET) |
|---|---|---|
| 3-3 | W-L | 4-1 |
| 0.0 | fWAR (FanGraphs) | 0.0 |
| 3.63 / 3.54 | ERA /xERA | 4.06 / 4.47 |
| 3.72 / 3.68 | FIP / xFIP | 5.01 / 4.96 |
| 1.40 | WHIP | 1.42 |
| 13.7 | K-BB% | 5.6 |
| 46.2 | GB% | 44.4 |
| 100 | Stuff+ | 109 |
| 108 | Location+ | 96 |
Giants vs Tigers Prediction, Betting Analysis
The Giants are short road underdogs against the AL Central-leading Detroit Tigers, but their moneyline is still in play for our very own Evan Abrams' system, "Road Dogs Interleague."
Detroit is currently on a three-game home winning streak, and it's 20-8 overall this season at Comerica Park. That includes two straight 3-1 victories over the Giants in the first two matchups of this three-game set.
San Francisco is looking to avoid the sweep on Wednesday and ditch its two-game losing streak in the process.
Well, this system, which is +$5,523 overall since it's inception, expects that to happen with Landen Roupp on the hill.
Pick: Giants ML -105
Moneyline
According to Evan Abrams' system, Giants moneyline is the play to make on this game.
Run Line (Spread)
There's no play for this game on the run line.
Over/Under
There's no play for this matchup on the total.
Giants vs Tigers Betting Trends
