The Baltimore Orioles host the Toronto Blue Jays in the first game of a doubleheader on September 23, 2026. The opening pitch from Oriole Park at Camden Yards is scheduled for 1:35 p.m. ET. The game will be broadcast on SNET.
The Orioles are favored by -120 on the moneyline and by -1.5 on the run line. The Blue Jays are +100 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find our MLB picks and Blue Jays vs Orioles prediction below, as well as probable pitchers, weather report, and more.
Blue Jays vs Orioles Prediction
- Blue Jays vs Orioles Pick: Orioles ML (-120)
Our Blue Jays vs Orioles best bet is on Baltimore to win outright. Make sure to find the best odds by checking our live MLB odds page, and download the Action Network app for more picks and analysis.
Blue Jays vs Orioles Odds
| Blue Jays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -205 | 7.5 100o / -120u | +100 |
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +165 | 7.5 100o / -120u | -120 |
- Blue Jays vs Orioles moneyline: Blue Jays +100, Orioles -120
- Blue Jays vs Orioles over/under: 7.5 (-100o / -120u)
- Blue Jays vs Orioles spread: Blue Jays +1.5 (-205), Orioles -1.5 (+165)
Blue Jays vs Orioles Probable Pitchers
| Max Scherzer (RHP, TOR) | Stat | Chris Bassitt (RHP, BAL) |
|---|---|---|
| 3-8 | W-L | 8-5 |
| 0.0 | fWAR (FanGraphs) | 0.9 |
| 6.07 / 4.33 | ERA / xERA | 4.64 / 4.94 |
| 5.48 / 5.47 | FIP / xFIP | 4.38 / 4.62 |
| 7.3 | K-BB% | 8.0 |
| 31.9 | GB% | 45.7 |
| .252 | BABIP | .332 |
| 94 | Stuff+ | 97 |
| 105 | Location+ | 101 |
Blue Jays vs Orioles MLB Betting Preview
Our PRO tools project an edge on the Orioles moneyline against the Blue Jays.
While the consensus line sits at -125, our model projects them at -136 for this game, representing a 2.1% edge against the market, making this our top projection for this matchup with a C grade on our system.
As a reminder, you can see all of Sean Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
Blue Jays vs Orioles Pick, Betting Analysis
The Orioles took the opener of this series on Monday, 4-3, and our new system, BARTOLO, also backs them to win the first part of their doubleheader today.
The model projects Baltimore for 3.90 runs, while it has Toronto at only 3.53 runs.
BARTOLO gives the edge to the Orioles bullpen, ranking them 8th in MLB, while the Blue Jays relievers are 10th.
It also accounts for Max Scherzer's awful season, and he will start for Toronto in Game 1.
If you want to dive deeper into this game, check out BARTOLO, Zerillo's PRO baseball tool that gives you access to all the input data he uses to project games every day.
Pick: Orioles ML (-120, Fanatics)
