Siena vs. Duke Odds & Betting Predictions - March 19, 2026

Siena at Duke

7:00 pm • CBS
65 - 71

Siena at Duke Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Siena
23-11
+26.5
+28.5-112
o137.5-110
+3500
Duke
32-2
u136.5
-28.5-107
u137.5-110
-20000
location pinThursday 7:00 p.m.
March 19, 2026
Bon Secours Wellness ArenaGreenville
Siena vs. Duke Expert Picks
Mike Calabrese
Mike Calabrese
Last 30d: 52-74-0 (-1.1u)
DUKE -7.5 (Live)+117
1.5u
Jeremiah Rose
Jeremiah Rose
Last 30d: 31-27-1 (-0.1u)
DUKE -6.5 (Live)-118
0.3u
Mike Calabrese
Mike Calabrese
Last 30d: 52-74-0 (-1.1u)
DUKE -7.5 (Live)-108
1.08u
Cam Is Money
Cam Is Money
Last 30d: 74-62-4 (+2.8u)
DUKE -5.5 (Live)-120
0.83u
Mike Calabrese
Mike Calabrese
Last 30d: 52-74-0 (-1.1u)
DUKE -6.5 (Live)-115
2.3u
JMann
JMann
Last 30d: 33-45-0 (-8.2u)
Under 146.5 (Live)-110
0.91u
Mjaybrod
Mjaybrod
Last 30d: 79-69-0 (+9.9u)
SIE u53.5-109
0.5u
Brick laying
Mike McNamara
Mike McNamara
Last 30d: 86-111-1 (+0.1u)
SIE +28.5-115
0.2u
YBK Picks.com
Last 30d: 41-38-2 (-14.7u)
SIE +28.5-105
0.95u
Collin Whitchurch
Collin Whitchurch
Last 30d: 70-121-1 (+7.5u)
C.Boozer u4.5 Ast+115
0.29u
Gilles Gallant
Gilles Gallant
Last 30d: 55-47-0 (+4.7u)
C.Boozer u4.5 Ast+122
0.61u
#Tailing @nick_giffen
Nick Giffen
Nick Giffen
Last 30d: 46-65-0 (+13.0u)
C.Boozer u4.5 Ast+122
0.61u
Projecting 4.1
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 277-258-8 (+0.5u)
SIE o53.5-110
0.28u
#EV
Doug Ziefel
Doug Ziefel
Last 30d: 208-270-16 (-10.4u)
G.Doty o14.5 Pts-125
0.5u
Brandon Kravitz
Brandon Kravitz
Last 30d: 88-97-0 (+1.4u)
Under 135.5-108
1u
OldSchool0909
Last 30d: 99-96-1 (+12.8u)
SIE +27.5-110
0.91u
Sean Zerillo
Sean Zerillo
Last 30d: 131-125-3 (+2.2u)
SIE +28.5-110
0.25u
Sandy Plashkes
Sandy Plashkes
Last 30d: 125-132-4 (-21.9u)
Under 136-110
1.1u
Mike Calabrese
Mike Calabrese
Last 30d: 52-74-0 (-1.1u)
C.Boozer u23.5 Pts-114
1u
Duke is down Ngongba II, Foster, playing with a short bench for the foreseeable future. That reads to me like Scheyer being incentivized to reduce Boozer’s minutes in a blowout. Siena has a decent low-major interior defense, they’re not playing matador defense in the lane and they don’t foul very much. Late in the season, they inserted Riley Mulvey into the starting lineup, and the seven-footer has made a big difference. Pre-Mulvey logging starter minutes: Siena 93rd in 2PT Defense, 128th in Defensive Rebounding. With Mulvey over 34 minutes per game as a starter? Those numbers bump up to 2nd in 2PT Defense, 90th in Defensive Rebounding. Small sample size, but still an impressive improvement. Last year, Duke was a huge favorite over Mt St. Mary’s, and Flagg only played 22 minutes and scored 14 points. The year before that, Filipowski and McCain were their leading scorers, and in their Tournament opener against Vermont they produced 3 points and 15 respectively. In Scheyer’s first year, Filipowski scored 6 against Oral Roberts.
JMann
JMann
Last 30d: 33-45-0 (-8.2u)
DUKE -27.5-118
1.2u
Duke ranks 99th percentile in guarding ball-handler out of P&R. That’s what Siena wants to do.
Matt Moore
Matt Moore
Last 30d: 23-53-0 (-9.5u)
DUKE -28.5-105
0.11u
Royals Props
Royals Props
Last 30d: 45-44-0 (-3.5u)
C.Boozer o22.5 Pts-106
1.06u
Stuck 🚨
Stuck 🚨
Last 30d: 53-53-2 (+1.7u)
SIE +29.5-110
0.36u
Will have this written up but this is a huge number for a limited possession game and not sure Duke will rush anybody back for R1. Just gotta defend without fouling since Siena has absolutely zero depth now. If so, can keep this within 25. Siena lives in midrange which is where Duke wants you and Coyle has found his shot again recently. Massive backdoor shot if needed too
Babs .
Babs .
Last 30d: 104-69-0 (+24.1u)
SIE +29.5-110
0.91u
Duck
Duck
Last 30d: 64-62-0 (-0.4u)
Under 136.5-110
0.45u

Siena vs. Duke Previews & Analysis

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Prop Odds Comparison

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Siena vs. Duke Public Betting Percentages

Away Logo

Siena

Public

80%

Bets%

20%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Duke
19-1511-128-315-131-0
Siena
20-149-711-716-124-2

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Duke
12-228-154-710-180-1
Siena
11-234-127-118-203-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Duke
32-2N/AN/A26-21-0
Siena
23-11N/AN/A21-72-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 15thUVAW 74-70-6.5 LO 139.5DUKE -295
Mar 14thCLEMW 73-61-10.5 WU 134.5DUKE -610
Mar 12thFSUW 80-79-17 LO 150.5DUKE -2800
Mar 7thUNCW 76-61-18.5 LU 147.5DUKE -3600
Mar 3rd@NCSTW 93-64-9.5 WO 150.5DUKE -500
Team Stats
25-65 (38%)
Field Goals
24-59 (41%)
6-6 (100%)
Free Throws
18-21 (86%)
9-26 (35%)
3P
5-26 (19%)
28
Rebounds
39
15
Assists
11
6
Turnovers
8
5
Steals
3
2
Blocks
3
16
Fouls
10

Siena vs. Duke Odds Comparison

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Siena at Duke Team Totals

MatchupOverUnder
Siena
23-11
N/A
N/A
Duke
32-2
N/A
N/A