Iowa State vs. Cincinnati Odds & Betting Predictions - October 4, 2025

Iowa State at Cincinnati

4:00 pm • ESPN2
30 - 38

Iowa State at Cincinnati Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Iowa State
5-1
-3.5
+1.5-108
o55.5-110
+100
Cincinnati
4-1
u54.5
-1.5-112
u55.5-110
-120
location pinSaturday 4:00 p.m.
October 04, 2025
Nippert StadiumCincinnati
Iowa State vs. Cincinnati Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 101-72-4 (+14.0u)
ISU +14 (Live)-115
0.5u
Sandy Plashkes
Sandy Plashkes
Last 30d: 84-104-3 (-0.6u)
CIN -125
1u
The Propfessor
The Propfessor
Last 30d: 35-53-2 (+2.8u)
R.Becht o17.5 Pass Comp-120
0.83u
Ryan Sura
Ryan Sura
Last 30d: 101-96-1 (+6.4u)
CIN -115
1.74u
Vegas Refund
Vegas Refund
Last 30d: 44-41-2 (-1.2u)
CIN -115
1u
Picks Office
Picks Office
Last 30d: 65-75-2 (-6.2u)
Over 54.5-110
0.91u
Firefighter Bets
Firefighter Bets
Last 30d: 140-128-1 (+1.4u)
CIN -125
0.8u
Big Bets On Campus (CFB)
Big Bets On Campus (CFB)
Last 30d: 73-71-2 (+2.3u)
CIN -1.5-112
0.89u
CIN o27.5 Team Total-125
0.8u
Duck
Duck
Last 30d: 90-75-0 (+4.3u)
Over 54.5-115
1u
Iowa state banged up in the secondary and very concerned about Cincinnati and their pass defense which gave up 440 pass yards last week on just 19 completions. Feel this one has a likelihood to be played in the 30s by both teams rather than the 20s. Should get over this total.
Babs .
Babs .
Last 30d: 86-76-1 (+8.9u)
CIN -120
0.83u
Collin Wilson
Collin Wilson
Last 30d: 101-72-4 (+14.0u)
CIN o27.5 Team Total-116
1u
Project Cincinnati 28.5 points; Iowa State sever issues against inside and outside zone read, 41% success rate or worse depending on personnel. Sorsby destroys Quarters coverage and has already seen two Power Four nickel packages this season. Cincy currently 19th quality drives, 6th offensive finishing drives
Cam Is Money
Cam Is Money
Last 30d: 65-83-3 (-16.6u)
CIN -125
0.8u
Mike Calabrese
Mike Calabrese
Last 30d: 23-40-0 (-18.5u)
CIN -1.5-110
1.36u
It’s October, time for Becht to turn into a 🎃
Stuck 🚨
Stuck 🚨
Last 30d: 55-63-2 (-0.5u)
CIN -1-110
0.45u

Iowa State vs. Cincinnati Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Iowa State vs. Cincinnati Public Betting Percentages

Away Logo

Iowa State

Public

39%

Bets%

61%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cincinnati
4-12-11-01-12-0
Iowa State
3-32-10-22-21-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cincinnati
4-13-01-02-01-1
Iowa State
3-32-11-12-21-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cincinnati
4-1N/AN/A2-01-1
Iowa State
5-1N/AN/A4-01-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 27th@KUW 37-34+5.5 WO 56.5CIN +172
Sep 13thNWSW 70-0-48.5 WO 55.5-
Sep 6thBGSUW 34-20-22.5 LO 46.5CIN -2200
Aug 29thNEBL 17-20+6 WU 50.5NEB +185
Nov 30thTCUL 13-20+2.5 LU 58.5TCU +114
Team Stats
465
Total Yards
474
86
Total Plays
59
5.406976744186046
Yards Per Play
8.033898305084746
314
YDS
214
30/48
Comps/Atts
13/25
6.541666666666667
YPA
8.56
2/0
TDs/INTs
2/0
4/15
Sacks/Yards
0/0
151
Rush Yards
260
38
Attempts
34
3.973684210526316
YPC
7.647058823529412
2
TDs
3
0
Fumbles Lost
1
0
Interceptions
0
4/6 66.67%
Redzone
4/4 100%
4/17 0%
3rd Down
4/11 0%
4/7 0%
4th Down
1/3 0%
29
Total
20
14
Pass
7
9
Rush
12
6
Penalty
1
8/60
Penalties/Yards
13/128

Iowa State vs. Cincinnati Odds Comparison

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Iowa State at Cincinnati Team Totals

MatchupOverUnder
Iowa State
5-1
o27.5-115
u27.5-115
Cincinnati
4-1
o28-113
u28-114