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LSU vs. Ole Miss Odds & Betting Predictions - September 27, 2025

LSU at Ole Miss

7:30 pm • ABC

LSU Tigers

4-0
@

Ole Miss Rebels

4-0

LSU at Ole Miss Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
LSU
4-0
-1.5
+1.5-108
o56.5-112
+105
Ole Miss
4-0
u56.5
-1.5-112
u56.5-108
-125
location pinSaturday 7:30 p.m.
September 27, 2025
Vaught-Hemingway StadiumOxford
thermometer image81°Fahrenheit
rain image0%Rain
wind image6Wind
LSU vs. Ole Miss Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 83-53-5 (+20.0u)
D.Wright Anytime TD Scorer Yes+262
0.5u
With Chambliss at QB, Lane will implement a ton of designed run using TE motion blockers. Expect Wright to be a top option in red zone after Chambliss has half dozen designed runs
Dan Gaspar
Dan Gaspar
Last 30d: 27-21-5 (+4.6u)
D.Alexander u46.5 Rec Yds-115
1.15u
Mjaybrod
Mjaybrod
Last 30d: 56-69-2 (-8.6u)
LSU o27.5 Team Total-105
1u
Nobody likes this LSU offense
Sandy Plashkes
Sandy Plashkes
Last 30d: 63-94-3 (-19.9u)
Over 54.5-110
1.1u
Tailing Lane Kiffen
Boomer Betz
Boomer Betz
Last 30d: 124-114-1 (+11.4u)
Under 54.5-107
1u
Cam Is Money
Cam Is Money
Last 30d: 50-59-1 (-10.8u)
Over 54.5-105
1u
Ryan Sura
Ryan Sura
Last 30d: 90-79-2 (+13.7u)
LSU -110
1.1u
Collin Wilson
Collin Wilson
Last 30d: 83-53-5 (+20.0u)
LSU -113
1.13u
From BBOC SEC Preview; LSU Nussmeier and elite stable of WRs to take on a depleted Ole Miss secondary. Tigers get SELA W4 while Ole Miss faces Tulane

LSU vs. Ole Miss Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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LSU vs. Ole Miss Public Betting Percentages

Away Logo

LSU

Public

Home Logo

Ole Miss

100%

Bets%

0%

Money%

NCAAF Public Betting Right Arrow

Betting Trends

  • Ole Miss are 4-0 in their last 5 games.
  • Ole Miss are 3-1 in their last 5 games against the spread
  • Ole Miss are 0-1 in their road games against the spread
  • The totals have gone OVER in 3 of Ole Miss' last 4 games
  • The totals have gone OVER in 2 of Ole Miss' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Ole Miss		3-13-00-13-1N/A
LSU		2-21-21-01-11-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Ole Miss		3-12-11-03-1N/A
LSU		1-31-20-10-20-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Ole Miss		4-0N/AN/A4-0N/A
LSU		4-0N/AN/A2-01-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 20thTULNW 45-10-12.5 WU 61.5MISS -440
Sep 13thARKW 41-35-3.5 WO 60MISS -172
Sep 6th@UKW 30-23-8.5 LO 50.5MISS -345
Aug 30thGASTW 63-7-33.5 WO 60.5MISS -15000
Jan 3rdDUKEW 52-20-18.5 WO 51.5MISS -1000
Team Stats

Passing

1100
YDS
1299
105/150
Comps/Atts
76/118
7.33
YPA
11.01
7/2
TDs/INTs
8/4
6/59
Sacks/Yards
4/15

Rushing

467
Rush Yards
874
125
Attempts
174
3.74
YPC
5.02
6
TDs
13

Turnovers

Fumbles Lost
2
Interceptions
4

Efficiency

14/17 82.4%
Redzone
24/25 96%
26/55 0%
3rd Down
26/49 0%
3/4 0%
4th Down
2/2 0%

First Downs

94
Total
102
57
Pass
43
24
Rush
50
13
Penalty
9

Misc

/
Penalties/Yards
/

LSU vs. Ole Miss Odds Comparison

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LSU at Ole Miss Team Totals

MatchupOverUnder
LSU
4-0
N/A
N/A
Ole Miss
4-0
N/A
N/A