USC vs. Oregon Odds & Betting Predictions - November 22, 2025

USC at Oregon

4:00 pm

USC Trojans

@

Oregon Ducks

MatchupOpenSpreadTotalMoneyline
USC 5-2	N/A	N/A	N/A
Oregon 7-1	N/A	N/A	N/A

location pin

Saturday 4:00 p.m.

November 22, 2025

Autzen StadiumEugene

No props found

NCAAF Public Betting

Oregon are 4-1 in their last 5 games.
Oregon are 3-2 in their last 5 games against the spread
Oregon are 2-1 in their road games against the spread
The totals have gone OVER in 2 of Oregon' last 5 games
The totals have gone OVER in 2 of Oregon' 5 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Oregon	5-3	3-2	2-1	3-2	1-0
USC	4-4	3-1	1-3	3-4	1-0

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Oregon	4-4	2-3	2-1	3-2	1-0
USC	4-4	3-1	1-3	4-3	0-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Oregon	7-1	N/A	N/A	4-1	1-0
USC	5-2	N/A	N/A	6-1	0-1

date	opponent	score	spread	over/under	moneyline
Oct 25th	WIS	W 21-7	-31.5 L	U 44.5	-
Oct 18th	@RUT	W 56-10	-18 W	O 62	ORE -1048
Oct 11th	IU	L 20-30	-6.5 L	U 51.5	IU -278
Sep 27th	@PSU	W 30-24	+4 W	O 52.5	ORE +158
Sep 20th	ORST	W 41-7	-33.5 W	U 58.5	-

Total

Passing

2283

YDS

1975

158/228

Comps/Atts

158/223

10.01

YPA

8.86

16/4

TDs/INTs

20/4

6/37

Sacks/Yards

11/74

Rushing

1427

Rush Yards

1896

242

Attempts

303

5.9

YPC

6.26

19

TDs

21

Turnovers

Fumbles Lost

4

Interceptions

4

Efficiency

33/36 91.7%

Redzone

30/34 88.2%

43/81 0%

3rd Down

50/101 0%

10/14 0%

4th Down

12/18 0%

First Downs

180

Total

185

98

Pass

83

64

Rush

91

18

Penalty

11

Misc

/

Penalties/Yards

/

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MatchupOverUnder
USC 5-2	N/A	N/A
Oregon 7-1	N/A	N/A