The NFL Divisional Round Saturday doubleheader concludes with a matchup between the Seattle Seahawks and San Francisco 49ers at Lumen Field in Seattle, Was. This game will broadcast live on FOX at 8 p.m. ET.
- For more NFL playoff coverage, check out our Seahawks vs 49ers preview, which includes five picks for tonight's NFC Divisional Round showdown.
Continue below for Divisional Round odds and my Seahawks vs 49ers parlay, which includes a moneyline pick and a player prop to pair with it.
Seahawks vs 49ers Parlay
- Seahawks Moneyline (-310)
- Christian McCaffrey 50+ Rush Yards (-157)
Parlay Odds: +120 (DraftKings)
Seahawks vs 49ers Odds
| Seahawks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-7 -105 | 44.5 -105o / -115u | -310 |
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+7 -115 | 44.5 -105o / -115u | +250 |
- Seahawks vs 49ers Moneyline: Seahawks -310, 49ers +250
- Seahawks vs 49ers Over/Under: 44.5 (-105o / -1115u)
- Seahawks vs 49ers Spread: Seahawks -7 (-105), 49ers +7 (-115)
Seahawks vs 49ers Preview, Parlay Picks
The San Francisco 49ers and Seattle Seahawks will clash on Saturday Night with a trip to the NFC Championship on the line.
Seattle earned the bye when it defeated the 49ers in the final week of the season.
San Francisco went into Philly last week and pulled off the upset, playing as six-point underdogs.
The 49ers' injury situation, however, got even worse last weekend when tight end George Kittle went down with a season-ending injury.
Seattle has issues of its own, as quarterback Sam Darnold reportedly hasn't thrown a football since Thursday due to an oblique injury.
Seahawks Moneyline (-310)

I still believe the Seahawks will earn the win tonight despite the Sam Darnold injury concerns.
The Seahawks' strong defensive unit will be the difference in this matchup. We saw two weeks ago how dominant their defense was against San Francisco, and now the 49ers will be missing one of their top playmakers in George Kittle.
San Francisco has too many key injuries to overcome when playing against one of the best defensive teams in the league.
Additionally, winning on the road in Seattle is always a challenge in the postseason.
Christian McCaffrey 50+ Rush Yards (-157)

We will team up with our Action Pro Report for this prop.
I expect the 49ers to lean on their running game due to the numerous injuries.
Christian McCaffrey has cashed this prop in six of his last eight games. He has rushed for 48 yards or more in eight straight games.
Our Action Pro Report projects him for 64 yards tonight.
Seahawks vs 49ers Parlay
- Seahawks Moneyline (-310)
- Christian McCaffrey 50+ Rush Yards (-157)
Parlay Odds: +120 (DraftKings)



















