The Tennessee Titans (2-11) and San Francisco 49ers (9-4) will meet in Week 15 of the NFL season on Sunday afternoon. Kickoff is set for 4:25 p.m. ET from Levi's Stadium in Santa Clara, California. The game will broadcast live on FOX.
The Niners are 12.5-point favorites over the Titans on the spread (49ers -12.5), with the over/under set at 44.5 total points. San Francisco is a -850 favorite to win outright on the moneyline, while the Tennessee is +575 to pull off the upset.
Let's get into my Titans vs. 49ers predictions and NFL picks for Sunday, December 14.
Titans vs 49ers Prediction, Picks
- Titans vs 49ers pick: First Quarter Under 9.5 Points (+100)
My 49ers vs. Titans best bet is on the first quarter under, with the best price currently available at FanDuel. However, make sure to find the best odds by checking our live NFL odds page.
Titans vs 49ers Odds for NFL Week 15
| Titans Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+12.5 -110 | 44.5 -110o / -110u | +575 |
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-12.5 -110 | 44.5 -110o / -110u | -850 |
Tennessee Titans vs San Francisco 49ers NFL Preview
It's safe to say that there have been some growing pains for the Titans' offense with Cam Ward under center. The top pick in this past year's draft has shown flashes, but, as with many rookies, consistency and efficiency have not been there.
The Titans have put the ball in Ward's hands frequently, as they throw it at the third-highest rate in the NFL. With that volume, Ward ranks 30th in completion percentage and 32nd in yards per pass.
In large part, this is a Titans offense that is neither aggressive nor efficient. Those two things only aid the 49ers' defense.
San Francisco's defense has not generated much pressure and has subsequently allowed plenty of completions. Although they have done a good job of minimizing those gains, that should remain the case against the Titans.
When the 49ers have the ball in this matchup, it's going to make you sweat our angle.
They run the fifth-fastest offense in the NFL, and face a Titans secondary that has been pummeled this season. Tennessee ranks 26th in opponent completion percentage allowed and 31st in yards per pass allowed.
Meanwhile, the 49ers' passing attack has been solid, sitting in fifth in completion percentage and 10th in yards per pass. However, the opportunity for big plays against this Titans defense is not as great as it seems.
Tennessee ranks 12th in ADOT allowed, which means most of the big plays against them have resulted from YAC. The 49ers rank 23rd in YAC per reception on the year.
On the ground, Christian McCaffrey has been healthy but very inefficient. He's averaged just 3.6 yards per carry, which is 43rd amongst running backs.
While the 49ers' offense may appear to have a strong matchup, stylistic clashes and overall inefficiency could hinder them early in this one.
Titans vs 49ers Betting Predictions, Analysis
First-quarter bets are always a sweat, as the window is tight, but this number has value.
We shouldn't expect the Titans to score early, so it will take two successful drives from the 49ers to get this over.
As noted above, the 49ers don't have the offensive traits to put together two scoring drives in the first 15 minutes.
They don't generate big plays, and their best offensive weapon is horribly inefficient on the ground.
Take the first quarter under.
Titans vs 49ers Best Bet
- First Quarter Under 9.5 Points (+100)
Titans vs 49ers Betting Trends
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