Padres vs. Cubs Odds & Betting Predictions - September 30, 2025

Padres at Cubs

7:08 pm • ABC
@
Starting Pitchers
pitcherteameraw-l
Matthew Boyd logoM.BoydChicago Cubs logo0.000-0
Nicholas Pivetta logoN.PivettaSan Diego Padres logo0.000-0

Padres at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
90-72
-1.5
+1.5-210
o6.5-124
+108
Cubs
92-70
u7
-1.5+182
u6.5+102
-127
location pinTuesday 7:08 p.m.
September 30, 2025
Wrigley FieldChicago
thermometer image75°Fahrenheit
rain image0%Rain
wind image8Wind
Padres vs. Cubs Expert Picks
💰🦡 Jake
💰🦡 Jake
Last 30d: 102-118-7 (+35.7u)
Over 3.5 (F5)-120
1.2u
YBK Picks.com
Last 30d: 38-40-0 (-10.6u)
CHC -130
2u
Lines at Lunch
Lines at Lunch
Last 30d: 85-79-3 (+1.6u)
M.Machado o1.5 Hits + Runs + RBIs-130
1.3u
M.Busch o1.5 Total Bases+142
0.7u
Ryan Sura
Ryan Sura
Last 30d: 100-92-2 (+8.6u)
M.Busch o1.5 Total Bases+142
1u
Kenny Ducey
Kenny Ducey
Last 30d: 28-22-2 (+4.6u)
CHC -130
1.3u
Picks Office
Picks Office
Last 30d: 63-88-4 (-21.7u)
CHC -120
1u
Lines at Lunch
Lines at Lunch
Last 30d: 85-79-3 (+1.6u)
M.Boyd o4.5 Hits Allowed-129
1.29u
SD +102
0.98u
Sandy Plashkes
Sandy Plashkes
Last 30d: 69-105-3 (-20.3u)
SD +102
1u
Boomer Betz
Boomer Betz
Last 30d: 130-100-2 (+44.2u)
CHC -108
1u
Cam Is Money
Cam Is Money
Last 30d: 52-68-3 (-15.6u)
M.Boyd u3.5 Ks+120
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 107-131-8 (+40.4u)
Under 7-109
1u
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Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 47-61-5 (-1.1u)
Under 7-106
1u
M.Boyd u14.5 Outs+140
1u
N.Pivetta u14.5 Outs+127
1u
M.Machado To Hit 1+ Home Runs Yes+466
0.25u
M.Machado To Record 2+ Total Bases Yes+113
1u
Sean Zerillo
Sean Zerillo
Last 30d: 144-183-4 (-16.8u)
CHC -110
0.55u
Bet to -125. Split with series price
Under 7-106
0.53u
Bet to -110
N.Pivetta u14.5 Outs+139
0.1u
Bet to +120
M.Boyd u14.5 Outs+155
0.1u
Bet to +125

Padres vs. Cubs Previews & Analysis

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    Pros Boldly Betting This Tuesday MLB Pick

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    Sep 30, 2025 UTC
  • Today's MLB Best Bets article feature image

    Today's MLB Best Bets

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    Sep 30, 2025 UTC
  • Padres vs Cubs: NL Wild Card Game 1 Best Bet article feature image

    Padres vs Cubs: NL Wild Card Game 1 Best Bet

    Tony Sartori
    Sep 30, 2025 UTC
  • Zerillo's Opening Pitch for Tuesday's Wild Card Games article feature image

    Zerillo's Opening Pitch for Tuesday's Wild Card Games

    Sean Zerillo
    Sep 30, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Padres vs. Cubs Public Betting Percentages

Away Logo

Padres

Public

100%

Bets%

0%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
79-8336-4543-3833-5045-32
Padres
82-7835-4547-3343-5737-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
75-81-634-46-141-35-540-39-434-41-2
Padres
81-74-544-34-237-40-351-44-528-28

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
92-7044-3739-4245-3837-40
Padres
4-345-3547-3358-4231-25

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 28thSTLW 2-0-1.5 WU 7CHC -155
Sep 27thSTLW 7-3-1.5 WO 9.5CHC -178
Sep 26thSTLW 12-1-1.5 WO 9CHC -184
Sep 25thNYML 5-8+1.5 LO 7.5NYM -103
Sep 25thNYMW 10-3+1.5 WO 7.5CHC -118

Cubs vs. Padres Injury Updates

Cubs Injuries

  • Michael Soroka
    SP

    Soroka is out with shoulder

    Out

  • Justin Steele
    SP

    Steele is out for season with elbow

    Out for Season

Padres Injuries

  • Joseph Musgrove
    SP

    Musgrove is out for season with elbow

    Out for Season

Padres vs. Cubs Starting Lineups
Padres Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Nicholas Pivetta logoRN.Pivetta, P13-52.870.9859.41
HITTERSAVGOBPSLGHR
Fernando Tatis logo1F.Tatis, RF.268.368.44625
Luis Arraez logo2L.Arraez, 1B.292.327.3928
Manuel Machado logo3M.Machado, 3B.275.335.46027
Jackson Merrill logo4J.Merrill, CF.264.317.45716
Xander Bogaerts logo5X.Bogaerts, SS.263.328.39111
Ryan O'Hearn logo6R.O'Hearn, DH.283.374.46313
Gavin Sheets logo7G.Sheets, LF.252.317.42919
Jacob Cronenworth logo8J.Cronenworth, 2B.246.367.37711
Freddy Fermin logo9F.Fermin, C.255.309.3393
Cubs Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Matthew Boyd logoLM.Boyd, P14-83.211.0917.71
HITTERSAVGOBPSLGHR
Michael Busch logo1M.Busch, 1B.261.343.52334
Nicholas Hoerner logo2N.Hoerner, 2B.297.345.3947
Ian Happ logo3I.Happ, LF.243.342.42023
Kyle Tucker logo4K.Tucker, DH.266.377.46422
Seiya Suzuki logo5S.Suzuki, RF.245.326.47832
Carson Kelly logo6C.Kelly, C.249.333.42817
Peter Crow-Armstrong logo7P.Crow-Armstrong, CF.247.287.48131
Dansby Swanson logo8D.Swanson, SS.244.300.41724
Matthew Shaw logo9M.Shaw, 3B.226.295.39413

Padres vs. Cubs Odds Comparison

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Padres at Cubs Team Totals

MatchupOverUnder
Padres
90-72
N/A
N/A
Cubs
92-70
N/A
N/A