The St. Louis Cardinals host the Baltimore Orioles on August 27, 2026. First pitch from Busch Stadium is scheduled for 2:15 p.m. EDT. The game will be broadcast on CARD.
The Orioles are favored by -112 on the moneyline and by -1.5 on the run line. The Cardinals are +104 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find my MLB picks and Orioles vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
Orioles vs Cardinals Prediction
- Orioles vs Cardinals Pick: Trevor Rogers Under 4.5 Strikeouts (+118)
My Orioles vs Cardinals best bet is on Trevor Rogers to record under 4.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Orioles vs Cardinals Odds
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +146 | 8.5 -100o / -122u | -112 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -176 | 8.5 -100o / -122u | +104 |
- Orioles vs Cardinals moneyline: Orioles -112, Cardinals +104
- Orioles vs Cardinals over/under: 8.5 (-100o / -122u)
- Orioles vs Cardinals spread: Orioles -1.5 (+146), Cardinals +1.5 (-176)
Orioles vs Cardinals Probable Pitchers
| Trevor Rogers (LHP, BAL) | Stat | TBD (STL) |
|---|---|---|
| 9-8 | W-L | — |
| 2.8 | fWAR (FanGraphs) | — |
| 4.14/3.86 | ERA / xERA | — |
| 3.62/4.17 | FIP / xFIP | — |
| 14.0% | K-BB% | — |
| 39.8% | GB% | — |
| .293 | BABIP | — |
| 102 | Stuff+ | — |
| 105 | Location+ | — |
Orioles vs Cardinals MLB Betting Preview
The Baltimore Orioles (65-68) travel to face the St. Louis Cardinals (66-68) on Thursday afternoon, wrapping up a three-game interleague series.
Baltimore comes off a thrilling 8-7 victory on Wednesday, propelled by Christian Encarnacion-Strand's impressive 4-hit performance.
The Orioles continue to rely on power to keep them competitive, ranking fourth in the American League with 163 home runs on the season. However, they carry a modest 31-34 record on the road as they look to seal a series win.
St. Louis finds itself navigating a difficult stretch, sitting at 32-36 at home and continuing to wrestle with depth issues in the rotation.
With both Andre Pallante and Hunter Dobbins sidelined on the injured list, the pitching staff has been pushed to its limits.
To cover the void, it seems the Cardinals are calling up left-hander Cooper Hjerpe to make his major league debut.
Offensively, St. Louis has stayed solid in getting on base, ranking ninth in the National League with a .316 OBP, with Alec Burleson leading the charge as he aims to extend his hitting streak to 13 games.
The Orioles hand the ball to Trevor Rogers, who has quietly put together a strong late-summer run. Rogers carries a 3-1 record with a quality start in three of his four August outings, stabilizing Baltimore’s starting staff.
Orioles vs Cardinals Pick, Betting Analysis
While Trevor Rogers has enjoyed a productive stretch on the mound, his prop lines are currently inflated relative to his projected strikeout efficiency.
Action PRO expect Rogers to fall well short of high strikeout totals in this spot, slating him for roughly 3.67 strikeouts against a disciplined Cardinals lineup that excels at getting on base.
Comparing this projection against the market consensus line of 4.5 strikeouts creates a significant 23.4% edge favoring the low side.
St. Louis makes consistent enough contact to limit extended strikeout sequences, making this value point an elite play.
Pick: Trevor Rogers Under 4.5 Strikeouts (+118)
