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White Sox vs Astros Prediction, Pick, MLB Odds for Tuesday, September 1

White Sox vs Astros Prediction, Pick, MLB Odds for Tuesday, September 1 article feature image
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Photo Credit: Denis Poroy-Imagn Images
Pictured: Ronel Blanco stands on the mound

The Houston Astros host the Chicago White Sox on September 1, 2026. First pitch from Daikin Park is scheduled for 8:10 p.m. EDT. The game will be broadcast on CHSN.

The White Sox are favored by -113 on the moneyline and by -1.5 on the run line. The Astros are -105 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and White Sox vs Astros prediction below, as well as probable pitchers, weather report, and more.


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White Sox vs Astros Prediction

  • White Sox vs Astros Pick: Ronel Blanco to Record the Win

My White Sox vs Astros best bet is on Blanco to record the win. Make sure to find the best odds by checking our live MLB odds page.


White Sox vs Astros Odds

White Sox Logo
September 1, 2026
8:10 p.m. EDT
CHSN
Astros Logo
White Sox Odds
SpreadTotalMoneyline
-1.5
-180
8.5
-105o / -115u
-113
Astros Odds
SpreadTotalMoneyline
+1.5
+150
8.5
-105o / -115u
-105
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • White Sox vs Astros moneyline: White Sox -113, Astros -105
  • White Sox vs Astros over/under: 8.5 (-105o / -115u)
  • White Sox vs Astros spread: White Sox -1.5 (+150), Astros +1.5 (-180)

White Sox vs Astros Probable Pitchers

Sean BurkeStatRonel Blanco
7-6W-L0-1
2.7fWAR (FanGraphs)-0.4
3.32 / 3.71ERA / xERA7.71 / 5.44
3.66 / 3.86FIP / xFIP6.94 / 4.98
18.1K-BB%7.9
34.4GB%40.3
.277BABIP.246
99Stuff+93
101Location+102

White Sox vs Astros MLB Betting Preview

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White Sox vs Astros Pick, Betting Analysis

Editor’s note: This article was transcribed from the latest episode of the Payoff Pitch Podcast.

By Derek Carty

Ronel Blanco to record the win at +324 at DraftKings, and I like it down to +250. A lot of times in this market, we see the books kind of give us really good odds when the pitcher is expected to not go super deep into the game, which makes sense because if you can't go five innings, you can't get the win.

Blanco has missed a bunch of time on the IL, has only made two rehab starts, and in his last one, he only threw 71 pitches. So I'm guessing that the books kind of see that and are thinking that he's going to have a hard time going five. But I don't think he's going to struggle as much to go five as the books think because, in his previous rehab start, he threw 85 pitches, and the 71-pitch start was kind of cut short because he gave up 10 runs. Hopefully, he is better than that tonight.

If he gives up 10 runs, he's certainly not going to get to five innings. But I do think his arm is built up enough to be capable of going five innings.

The White Sox offense has been scuffling the last couple of days. So definitely a chance there for Blanco at +324 to record a win.

Pick: Ronel Blanco to Record the Win


White Sox vs Astros Weather


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