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Guardians vs Angels Prediction, Pick, MLB Odds for Tuesday, August 25

Guardians vs Angels Prediction, Pick, MLB Odds for Tuesday, August 25 article feature image
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Pictured: Tyler Heineman. (Credit: Justine Willard-Imagn Images)

The Los Angeles Angels host the Cleveland Guardians on August 25, 2026. First pitch from Angel Stadium is scheduled for 9:38 p.m. EDT. The game will be broadcast on CLEG.

The Guardians are favored by -140 on the moneyline and by -1.5 on the run line. The Angels are +131 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find my MLB picks and Guardians vs Angels prediction below, as well as probable pitchers, weather report, and more.


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Guardians vs Angels Prediction

  • Guardians vs Angels Pick: Tyler Heineman Under 0.5 Hits + Runs + RBIs (-118 or Better)

My Guardians vs Angels best bet is on Tyler Heineman to record under 0.5 Hits + Runs + RBIs. Make sure to find the best odds by checking our live MLB odds page.


Guardians vs Angels Odds

Guardians Logo
Tuesday, Aug 25
9:38 p.m. ET
CLEG
Angels Logo
Guardians Odds
SpreadTotalMoneyline
-1.5
+123
7.5
102o / -123u
-140
Angels Odds
SpreadTotalMoneyline
+1.5
-149
7.5
102o / -123u
+131
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Guardians vs Angels moneyline: Guardians -140, Angels +131
  • Guardians vs Angels over/under: 7.5 (+102o / -123u)
  • Guardians vs Angels spread: Guardians -1.5 (+123), Angels +1.5 (-149)

Guardians vs Angels Probable Pitchers

Gavin Williams (RHP, CLE)StatWalbert Urena (RHP, LAA)
12-7W-L8-9
2.8fWAR (FanGraphs)1.8
3.72/3.91ERA / xERA2.80/3.31
3.58/2.86FIP / xFIP3.74/4.21
24.6%K-BB%10.4%
43.4%GB%53.5%
.276BABIP.250
105Stuff+100
105Location+102

Guardians vs Angels MLB Betting Preview

By Derek Carty

Editor's Note: This written best bet is a transcription from the latest episode of the Payoff Pitch podcast.

Tyler Heineman Under 0.5 Hits + Runs + RBIs is the best play on the board for this matchup, and I like it down to -118.

To start with, Heineman is not a good hitter. He's hitting .179 this year, and THE BAT X projects him at .203 going forward.

He's facing a really good pitcher today in Gavin Williams, with one of the best pitch-framing catchers in baseball, Patrick Bailey, behind the plate.

There’s also an extreme pitcher's umpire behind the plate, along with about a 20% chance he gets pinch-hit for once the bullpen comes in.

Add it all up, and this one is showing some good value.

Pick: Tyler Heineman Under 0.5 Hits + Runs + RBIs (-118 or Better)


Guardians vs Angels Weather


Get the latest coverage on MLB Weather.


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