The Boston Red Sox host the Colorado Rockies on Wednesday, July 9, 2025. First pitch from Fenway Park is scheduled for 7:10 p.m. ET; the game will be broadcast on NESN and MLB.TV.
The Red Sox enter as massive favorites of -305, while the Rockies are up at +245 to pull off the upset. The over/under, meanwhile, comes in at 9 total runs.
Find my Rockies vs Red Sox prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.
Rockies vs Red Sox Prediction
- Rockies vs. Red Sox Pick: Under 9
My Red Sox vs. Rockies best bet is on both teams to go under the total. Make sure to find the best odds by checking our live MLB odds page.
Rockies vs Red Sox Odds
| Rockies Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
+2.5 -118 | 9 -105o / -115u | +270 |
| Red Sox Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
-2.5 -102 | 9 -105o / -115u | -325 |
Rockies vs Red Sox Projected Starting Pitchers
Rockies vs Red Sox MLB Betting Preview
Wednesday's Rockies vs. Red Sox interleague matchup fits a historically profitable betting system from our Bet Labs database.
Called "Unders with Soft Starters and Neutral Winds," this system targets unders in regular-season MLB games where softer home starting pitchers — starters with low strikeout rates and moderate WHIPs —are on the mound in Games 3 or 4 of a series.
By this point in the series, hitters have seen multiple arms, and scouting reports are sharper, yet scoring remains muted when the matchup lacks overpowering velocity and winds remain neutral.
The setup avoids exaggerated run environments by filtering out strong directional wind influence, keeping offensive surges in check.
With the home team in the middle of the season grind and winning at a modest clip, the market may overlook how often these quiet conditions lead to slower-paced, low-scoring outcomes.
Rockies vs Red Sox Pick, Betting Analysis
According to Action Network's PRO Report, the under for this game has already taken four sharp moves. In fact, at some sportsbooks, the line has moved to 8.5, so it may be worth grabbing an under 9 while it's still available.
Given the weather at play and the historically profitable betting system at hand, we're going to ride with the under on Wednesday night.
Pick: Under 9
Moneyline
We don't have a bet on either side for Wednesday's interleague matchup between the Rockies and Red Sox.
Run Line (Spread)
Like the moneyline, we're staying away from a bet on the run line in this game.
Over/Under (Total)
Our best bet for this game is for both teams to go under the total. With the historically profitable system at hand and the favorable weather, we'll take a shot on the over/under.
