The Chicago White Sox host the Detroit Tigers on on June 5, 2025. First pitch from Rate Field is scheduled for 2:10 p.m. ET; the game will be broadcast on FDSDET.
Find my MLB betting preview and Tigers vs White Sox prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Tigers vs White Sox Prediction
- Tigers vs White Sox picks: Tigers -1.5
My Tigers vs White Sox best bet is on the Tigers run line. Make sure to find the best odds by checking our live MLB odds page.
Tigers vs White Sox Odds
| Tigers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -125 | 8.5 -105o / -115u | -210 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +105 | 8.5 -105o / -115u | +170 |
Tigers vs White Sox Projected Starting Pitchers
| Casey Mize (DET) | Stat | Sean Burke (CWS) |
|---|---|---|
| 6-1 | W-L | 3-6 |
| 0.7 | fWAR (FanGraphs) | 0.0 |
| 2.82 / 3.11 | ERA /xERA | 4.20 / 5.46 |
| 4.05 / 3.84 | FIP / xFIP | 5.27 / 5.31 |
| 1.14 | WHIP | 1.42 |
| 15.9 | K-BB% | 5.3 |
| 43 | GB% | 34.3 |
| 97 | Stuff+ | 92 |
| 103 | Location+ | 98 |
Tigers vs White Sox Prediction, Betting Analysis
By: Brit Devine
The Tigers should be able to cruise to a victory in this one thanks to huge starting pitching and offensive advantages.
Casey Mize has looked great for the Tigers this season. White Sox starting pitcher Sean Burke has had some moments, but he's a clear step down compared to how well Mize has been throwing the ball.
The Tigers' offense has been a little above league average over the last 30 days against right-handed pitching, while the White Sox rank last in wOBA in that span against righties.
With how good Mize has been, and with his advanced metrics backing that up, it might only take a few runs from the Tigers to get us across the finish line.
Pick: Tigers -1.5
If you're looking for more MLB picks from Scores and Odds, click here.
Moneyline
There's no play on the moneyline for this AL Central matchup.
Run Line (Spread)
Take the Tigers on the run line.
Over/Under
There's no play on the total, either.
