The Cleveland Guardians (86-72) host the Detroit Tigers (85-73) on September 25, 2025. First pitch from Progressive Field is scheduled for 6:40 p.m. EDT; the game will be broadcast on CLEG.
Find my MLB betting preview and Tigers vs Guardians prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Tigers vs Guardians Prediction
- Tigers vs Guardians pick: Under 8
My Tigers vs Guardians best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.
Tigers vs Guardians Odds
| Tigers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -140 | 8 -105o / -115u | +145 |
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +120 | 8 -105o / -115u | -170 |
Tigers vs Guardians Projected Starting Pitchers
| RHP Troy Melton (DET) | Stat | LHP Parker Messick (CLE) |
|---|---|---|
| 3-2 | W-L | 3-0 |
| 0.1 | fWAR (FanGraphs) | 1.3 |
| 2.79/3.76 | ERA /xERA | 2.08/2.65 |
| 4.64/4.27 | FIP / xFIP | 2.16/3.11 |
| 1.00 | WHIP | 1.30 |
| 13.3% | K-BB% | 18.3% |
| 45.2% | GB% | 49.1% |
| 106 | Stuff+ | 96 |
| 98 | Location+ | 111 |
Tigers vs Guardians Prediction, Betting Analysis
Game 3 of this AL Central clash features the Cleveland Guardians (-170) hosting the Detroit Tigers (+145). The over/under is 8 total runs, and after two Cleveland wins (5-2, 5-1), another pitching duel seems likely.
Troy Melton starts for Detroit, while Parker Messick takes the mound for Cleveland. Messick has been dominant at home this season, posting a 0.69 ERA in two starts, making a low-scoring game probable.
Detroit has dropped eight straight and is under pressure to stay in the division race, while Cleveland carries momentum and a tiebreaker advantage.
This matchup fits Evan Abrams’ “Contrarian Unders for Winning Teams, Later in Series” system: both squads have winning records, it’s later in the series, and public betting heavily favors the over. With under-support low, there’s contrarian value.
Pick: Under 8 (-115, bet365)
Tigers vs Guardians Betting Trends
