The Los Angeles Dodgers (60-43) and Boston Red Sox (55-49) will face off in the MLB tonight. First pitch from Fenway Park is scheduled for 7:10 p.m. ET. The game will broadcast live on SportsNet LA and MLB.TV.
Los Angeles is a -115 favorite to win outright on the moneyline, while Boston is -105 to pull off the upset. The over/under is set at 9.5 total runs.
Continue below for my Dodgers vs Red Sox predictions and MLB picks for Friday, July 25, as well as probable pitchers, betting trends, injury reports and more.
Dodgers vs Red Sox Picks, Prediction
- Dodgers vs. Red Sox pick: First Five Innings Under 5.5 Runs (-130)
My Red Sox vs. Dodgers best bet is on the first five innings under, with the best line currently available at DraftKings. But as always, make sure to find the best odds by checking our live MLB odds page.
Dodgers vs Red Sox Odds for Friday, July 25
| Dodgers Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 +135 | 9.5 -110o / -110u | -115 |
| Red Sox Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -160 | 9.5 -110o / -110u | -105 |
Dodgers vs Red Sox Projected Starting Pitchers
Los Angeles Dodgers vs Boston Red Sox MLB Betting Preview
Friday's Dodgers vs. Red Sox matchup fits a historically profitable betting system in our Bet Labs database.
This MLB first five innings system titled "Low Total Unders With Line Movement (F5)" is built around early-game environments where oddsmakers and sharp bettors anticipate limited scoring.
The foundation starts with a low F5 total — between 3.5 and 6.5 — indicating a strong pitcher’s duel or poor hitting conditions.
If the full-game total has moved down between a half-run and one run from open to close, it signals smart money pushing the market toward the under.
The model further refines this edge by requiring the juice on the under to remain within a sharp range, typically between -120 and -149, avoiding inflated pricing that could distort value.
Games played in modest wind conditions — between four and nine miles per hour — are included, as they often suppress offense without triggering dramatic public reaction.
By isolating games across the past three seasons and targeting first-half unders in tightly-lined, downward-trending markets, this system captures value where the market signals defensive control without overreaction.
This system boasts an all-time record of 282-215-5, good for a winning percentage of 57%. In 2025, that record moves to 82-42 (66%) with an ROI of 17%.
Red Sox' starter Brayan Bello boasts a solid ERA of 3.23 on the season, and while Dodgers starter Emmet Sheehan has a higher ERA at 4.41, his expected ERA (xERA) comes in at a much more respectable 3.66.
Given the looming positive regression for Sheehan and the system at play, we'll take the under in the first five innings here.
Dodgers vs Red Sox Best Bet
- F5 Under 5.5 (-130)
Moneyline
We don't have a bet on either side in this Dodgers vs. Red Sox showdown.
Run Line (Spread)
Like the moneyline, we're staying away from the run line here.
Over/Under
While we don't have a bet on the full-game under, our top play with this system is for both teams to go under the total in the first five innings.
Dodgers vs Red Sox Betting Trends
For the latest on MLB injuries, be sure to check out our MLB Injury Report page.
