The last Division Series game is on the schedule for Saturday, October 11. The Brewers will host the Cubs in Milwaukee in Game 5 of the NLDS after losing twice in Chicago.
Our MLB betting experts and systems have looked over today's odds and have made three picks, so continue reading for today's MLB best bets.
MLB Best Bets Today
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 8:08 p.m. | |
| 8:08 p.m. | |
| 8:08 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Sean Paul's Cubs vs Brewers Best Bet: Can the Cubs Finish the Job?
By Sean Paul
It'll be interesting to see which path the Cubs take on the mound. Going with Shota Imanaga doesn't seem like the best one, so that's an instant plus on the Cubs side.
Personally, I'd go with Collin Rea — on a very short leash — which is the case for any pitcher in a do-or-die game.
Michael Busch, leading off, has been a total game-changer, and the Brewers need to find a way to contain him. Busch is providing the power, but don't sleep on Kyle Tucker getting on base. He has a .429 OBP through seven playoff games, despite homering just once. Tucker and Busch are two of four Cubs starters with an OPS over .800 in this postseason.
The Brewers have a lot of options for their game five starters, but I don't love any of them. Jose Quintana probably should start to try to contain Busch in his first at-bat. The issue is that Quintana had a 5.18 xERA compared to a 3.96 ERA. Another option is Jacob Misiorowski, who tossed three scoreless innings earlier this series.
My larger concern is one that looked foolish for much of the regular season, but maybe it now matters: The Brewers just can't hit for power.
Neither team has its best pitcher going — and since the Cubs already conquered Freddy Peralta, this series feels like Chicago's to lose, even in Milwaukee.
The team I trust to score more in the bigger moments is the one to pick in a must-win game. That's the Cubs here.
Pick: Cubs ML +120 (play to -115)
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PRO's Cubs vs Brewers Best Bet: Back Kyle Tucker Tonight
By Action PRO
PRO projects Cubs DH Kyle Tucker with 1.11 hits tonight, which represents a nice 5.5% edge against the market.
Although Tucker struggled at times during the regular season, he has been great again in the playoffs, hitting .304 in this NL Division Series and .350 over his last six games.
The lefty slugger had two hits in each of the Cubs' home games on Wednesday and Thursday.
In this decisive matchup, you can back Tucker to get another hit against the Brewers.
Pick: Kyle Tucker 1+ Hits (-160)
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Bet Labs' Cubs vs Brewers Best Bet: System Recommends the Under
By Bet Labs
The "Contrarian Unders for Winning Teams, Later in Series" system targets unders in MLB series games (Game 2 or later) where both teams have winning records, suggesting quality pitching and competitive matchups.
However, public betting leans toward the over — likely expecting fireworks between top teams — which creates contrarian value on the under.
By capitalizing on low public support for the under (≤35%), the strategy fades public perception in favor of market inefficiencies, especially when bettors overestimate offensive output late in a series.
Pick: Under 7.5 (-115)
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