MLB Predictions Thursday, Best Bets, Prop Picks Today — September 4 article feature image
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MLB Predictions Thursday, Best Bets, Prop Picks Today — September 4

There are just 6 games on the MLB calendar for Thursday, September 4, but that didn't stop our MLB systems and betting experts from finding betting value.

So, continue reading as today's MLB best bets are below.

Quickslip

MLB Best Bets Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Philadelphia Phillies LogoMilwaukee Brewers Logo
4:10 p.m.
Chicago White Sox LogoMinnesota Twins Logo
7:40 p.m.
New York Yankees LogoHouston Astros Logo
7:40 p.m.
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.

Bet Labs' Phillies vs Brewers Best Bet: System Suggests Under

Philadelphia Phillies Logo
Thursday, September 4
4:10 p.m. ET
MLB.TV
Milwaukee Brewers Logo
Under 8 (-118)
DraftKings  Logo

By Bet Labs

This system targets unders in MLB series games (game two or later) in which both teams have winning records, suggesting quality pitching and competitive matchups. However, it also looks for games in which public betting leans toward the over — likely expecting fireworks between top teams — which creates contrarian value on the under. By capitalizing on low public support for the under (≤35%), the strategy fades public perception in favor of market inefficiencies, especially when bettors overestimate offensive output late in a series.

Overall, this system has generated a 5% ROI as it has cashed 54% of its picks (1369-1161-110). This season, the system has cashed 54% of its picks (137-118-10) and generated a 3% ROI.

MLB Icon
Evan Abrams – Contrarian Unders for Winning Teams, Later in Series
the game is played during the Regular or Postseason season
betting on the Under
the home team's win percentage is between 51% and 100%
the visitor team's win percentage is between 51% and 100%
the over/under % is between 0% and 35%
the series game # is between 2 and 100
$14,071
WON
1369-1161-110
RECORD
54%
WIN%

Pick: Under 8 (-118)


Bet Labs' White Sox vs Twins Best Bet: Where Will the Runs Come From?

Chicago White Sox Logo
Thursday, September 4
7:40 p.m. ET
MLB.TV
Minnesota Twins Logo
Under 8.5 (-110)
FanDuel Logo

By Bet Labs

"Weather Watch Unders" is a system built for MLB totals bettors who understand how environmental factors quietly shift run production. This approach keys in on games with moderate to strong winds — especially those blowing in or cross-field — paired with mild to cool temperatures, a known recipe for stifled fly balls and reduced scoring.

When totals open high, but tick down before first pitch, it signals sharp money reacting to these same weather cues. With home moneyline ranges excluding extreme mismatches, the model focuses on fairly priced contests where weather truly has a chance to swing scoring. Layer in the context of regular-season motivation, and this strategy captures overlooked market inefficiencies in totals inflated by prior offensive output rather than conditions on the field.

Overall, this system is 1543-1253-151 (55) and has generated a 6% ROI. This season, that ROI has jumped up to 12% as this system has cashed 59% of its picks (70-49-3).

MLB Icon
Evan Abrams / Bet Labs – Weather Watch Unders
the home money is between -206 and 150
the average wind speed is between 6 and 27 mph
the o/u change from open to close is between -2.5 and 0
the closing total is between 8 and 10.5
the temperature is between 30 and 70 degrees
the wind direction is From Left or In or None or From Right or Left to Right or Left To Right or Right To Left
betting on the Under
the game is played during the Regular season
$18,748
WON
1545-1253-151
RECORD
55%
WIN%

Pick: Under 8.5 (-110)



Tony Sartori's Yankees vs Astros Best Bet: Back Both Pitching Staffs

New York Yankees Logo
Thursday, September 4
7:40 p.m. ET
MLB.TV
Houston Astros Logo
Under 8.5 (-102)
BetMGM Logo

By Tony Sartori

Following Cristian Javier is a bullpen that ranks in the top 10 in ERA, xFIP and wins above replacement (WAR). The main concern in taking the under in this matchup is New York’s powerhouse lineup.

That said, Javier is capable of handling the task. Through 66 combined plate appearances against him, the current Yankees roster has a .180 batting average and .195 xBA.

Pick: Under 8.5 (-102)




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About the Author
Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

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