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Pirates vs Tigers Prediction, Pick, MLB Odds for Saturday, September 26

Pirates vs Tigers Prediction, Pick, MLB Odds for Saturday, September 26 article feature image
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Pictured: Justin Verlander speaks during Justin Verlander career celebration. (Credit: USA TODAY Network via Reuters Connect)

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The Detroit Tigers host the Pittsburgh Pirates on September 26, 2026. First pitch from Comerica Park is scheduled for 1:10 p.m. EDT. The game will be broadcast on DSN.

The Pirates are -105 on the moneyline and -1.5 on the run line. The Tigers are -115 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find our MLB picks and Pirates vs Tigers prediction below, as well as probable pitchers, weather report, and more.


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Pirates vs Tigers Prediction

  • Pirates vs Tigers Pick: Justin Verlander Under 5.5 Strikeouts (-160)

Our Pirates vs. Tigers best bet is on Justin Verlander to go under his strikeouts prop in the final game prior to his retirement. Make sure to find the best odds by checking our live MLB odds page. Be sure to download the Action Network app for more picks and analysis.


Pirates vs Tigers Odds

Pirates Logo
Saturday, Sep 26
1:10 p.m. ET
DSN
Tigers Logo
Pirates Odds
SpreadTotalMoneyline
-1.5
+160
8.5
-105o / -115u
-105
Tigers Odds
SpreadTotalMoneyline
+1.5
-190
8.5
-105o / -115u
-115
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Pirates vs Tigers moneyline: Pirates -105, Tigers -115
  • Pirates vs Tigers over/under: 8.5 (-105o / -115u)
  • Pirates vs Tigers spread: Pirates -1.5 (+160), Tigers +1.5 (-190)

Pirates vs Tigers Probable Pitchers

Kirby Yates (RHP, PIT)StatJustin Verlander (RHP, DET)
2-5W-L0-1
0.5fWAR (FanGraphs)-0.1
3.32/3.41ERA / xERA12.27/11.51
3.25/4.10FIP / xFIP7.74/7.07
18.0%K-BB%-5.3%
32.7%GB%18.8%
.290BABIP.333
88Stuff+101
99Location+77

Pirates vs Tigers MLB Betting Preview

Detroit arrives at the final weekend of the regular season sitting at 74-85 overall, holding a 40-38 mark on their home turf.

While postseason ambitions are off the table for the host club, there is no shortage of motivation at Comerica Park as fans gather to honor Justin Verlander in the final start of his legendary career.

Detroit claimed the series opener on Friday in an 8-7 thriller, anchored by a huge performance from Spencer Torkelson, who drove in three runs and crushed a home run.

Pittsburgh comes into Saturday's contest at 81-78 overall with a 37-41 record away from home.

Taking the mound for the Pirates is 39-year-old veteran Kirby Yates, who is set to make his first career Major League start after spending 12 seasons in the majors exclusively as a reliever, accumulating 517 bullpen appearances and 101 saves.

On the other side, Verlander makes his highly emotional return to the bump for his final appearance in a Tigers uniform prior to his retirement.


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Pirates vs Tigers Pick, Betting Analysis

According to the Action PRO projections, Justin Verlander is modeled for just 3.31 strikeouts in his final outing against Pittsburgh.

Comparing that projection against his current strikeout prop line of over/under 5.5 yields a substantial 26.6% edge toward the under.

That massive discrepancy earns an A+ grade in the system, making Verlander Under 5.5 Strikeouts the top value play for this matchup.

Pick: Justin Verlander Under 5.5 Strikeouts (-160)


Pirates vs Tigers Weather


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