Pirates vs Cardinals Prediction, Pick, Odds for Thursday, August 28

Pirates vs Cardinals Prediction, Pick, Odds for Thursday, August 28 article feature image
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Pictured: Miles Mikolas. (Credit: Kim Klement Neitzel-Imagn Images)

The St. Louis Cardinals (65-69) and Pittsburgh Pirates (59-75) will face off in the MLB today. First pitch from Busch Stadium is scheduled for 2:15 p.m. ET The game will broadcast live on SportsNet PT.

St. Louis is a -123 favorite to win outright on the moneyline, while Pittsburgh is +101to pull off the upset. The over/under is set at 8.5 total runs.

Continue below for my Pirates vs Cardinals prediction and MLB picks for Thursday, August 28, as well as probable pitchers, betting trends, injury reports and more.

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Our Pirates vs Cardinals Prediction

  • Pirates vs Cardinals pick: Under 8.5 Runs

Our Cardinals vs. Pirates best bet is on the under total runs, with the best price currently available at BetMGM. But as always, make sure to find the best odds by checking our live MLB odds page.


Pirates vs Cardinals Odds

Pirates Logo
Thursday, Aug 28
2:15 p.m. ET
SportsNet PT
Cardinals Logo
Pirates Odds
SpreadTotalMoneyline
-1.5
+161
8.5
-105o / -116u
+101
Cardinals Odds
SpreadTotalMoneyline
+1.5
-199
8.5
-105o / -116u
-123
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Pirates vs Cardinals Projected Starting Pitchers

RHP Braxton Ashcraft (PIT)StatRHP Miles Mikolas (STL)
4-2W-L6-10
1.1fWAR (FanGraphs)0.3
2.70/3.30ERA /xERA5.17/5.39
2.52/3.49FIP / xFIP5.01/4.85
1.18WHIP1.36
15.0%K-BB%9.2%
51.9%GB%39.8%
105Stuff+87
101Location+107

Pirates vs Cardinals Preview, Picks

The St. Louis Cardinals look to even their four-game set with the Pittsburgh Pirates after dropping back-to-back contests. Pittsburgh has taken Games 2 and 3, including a 2-1 win on Wednesday behind a clutch two-run single from Tommy Pham in the sixth inning.

Thursday’s finale features Braxton Ashcraft for the Pirates against veteran Miles Mikolas for the Cardinals.

The total sits at 8.5, and this game fits neatly into Evan Abrams’ “Steam Unders with Low OU Support” system. This angle identifies MLB regular season matchups (2019–2025) where sharp money has steamed the total down in the 8–10 run range, even as the betting public leans heavily toward the over.

With mild playing conditions and both teams coming off recent games landing close to the number (7–6, 8–3, 2–1), this contest checks all the filters: no extreme streaks, no weather anomalies, and sharp-vs-public disagreement in play.

Given Mikolas’ ability to suppress runs, the Pirates’ uneven offense outside of timely hits, and the systemic support for contrarian unders, the Under 8.5 emerges as the most valuable angle on the board.

MLB Icon
Evan Abrams / Bet Labs – Steam Unders with Low OU Support
the game was played during the 2025 or 2024 or 2023 or 2022 or 2021 or 2020 or 2019 season
the visitor team's 3 Games OU Margin is between -2.3 and 5.25
the home team's 3 Games OU Margin is between -3.33 and 3.19
the temperature is between 1 and 87 degrees
the o/u change from open to close is between -1.5 and 0
the closing total is between 8 and 10
the difference between money % and ticket % is between 1 and 87
the over/under % is between 1% and 29%
betting on the Under
the game is played during the Regular season
$13.515
WON
556-387-47
RECORD
59%
WIN%

Pirates vs Cardinals Best Bet

  • Under 8.5 (-120, Fanatics)

Pirates vs Cardinals Betting Trends


Pirates vs Cardinals


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