The St. Louis Cardinals host the San Diego Padres on June 17, 2026. First pitch from Busch Stadium is scheduled for 2:15 p.m. EDT. The game will be broadcast on CARD.
The Cardinals are favored by -121 on the moneyline and by -1.5 on the run line. The Padres are +103 on the moneyline and +1.5 on the run line. The total is set at 10.5 runs.
Find my MLB picks and Padres vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
Padres vs Cardinals Prediction
- Padres vs Cardinals Pick: Under 10.5 (-115, DraftKings)
My Padres vs Cardinals best bet is under 10.5 total runs. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Cardinals Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +160 | 10.5 -105o / -117u | +103 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -190 | 10.5 -105o / -117u | -121 |
- Padres vs Cardinals moneyline: Padres +103, Cardinals -121
- Padres vs Cardinals over/under: 10.5 (-105o / -117u)
- Padres vs Cardinals spread: Cardinals -1.5 (+160 ), Padres +1.5 (-190)
Padres vs Cardinals Probable Pitchers
| TBD | Stat | Kyle Leahy |
|---|---|---|
| W-L | 5-3 | |
| fWAR (FanGraphs) | 0.2 | |
| ERA / xERA | 4.64 / 6.58 | |
| FIP / xFIP | 4.66 / 4.33 | |
| K-BB% | 10.4 | |
| GB% | 42.8 | |
| BABIP | .338 | |
| Stuff+ | 89 | |
| Location+ | 105 |
Padres vs Cardinals MLB Betting Preview
Padres vs Cardinals Pick, Betting Analysis
By Justin van Zuiden
This is a wild total. The Padres rank dead last in the major leagues in team wOBA this season. They have scored just two total runs in the first two games of this series.
They may be throwing a bullpen game today, which is fine given the overall strength of that unit. Even without Mason Miller, who is on the bereavement list, there's plenty of talent in the bullpen, and they haven't used their better arms much so far in this series.
I simply do not see this turning into a shootout, and a double-digit total is giving far too much credit to the current state of San Diego's offense.
Pick: Under 10.5 (-115, DraftKings)
