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Cardinals vs Cubs Prediction, Pick, MLB Odds for Sunday, July 5

Cardinals vs Cubs Prediction, Pick, MLB Odds for Sunday, July 5 article feature image
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Photo Credit: Brett Davis-Imagn Images
Pictured: Alec Burleson celebrates with teammates

The Chicago Cubs host the St. Louis Cardinals on July 5, 2026. First pitch from Wrigley Field is scheduled for 2:30 p.m. EDT. The game will be broadcast on Peacock.

The Cubs are favored by -150 on the moneyline and by -1.5 on the run line. The Cardinals are +125 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Cardinals vs Cubs prediction below, as well as probable pitchers, weather report, and more.


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Cardinals vs Cubs Prediction

  • Cardinals vs Cubs Pick: Alec Burleson Over 1.5 Hits (+202, bet365)

My Cardinals vs Cubs best bet is a Burleson prop. Make sure to find the best odds by checking our live MLB odds page.


Cardinals vs Cubs Odds

Cardinals Logo
July 5, 2026
2:30 p.m. EDT
Peacock
Cubs Logo
Cardinals Odds
SpreadTotalMoneyline
+1.5
+136
8
-105o / -113u
+125
Cubs Odds
SpreadTotalMoneyline
-1.5
-165
8
-105o / -113u
-150
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Cardinals vs Cubs moneyline: Cardinals +125, Cubs -150
  • Cardinals vs Cubs over/under: 8 (-105o / -113u)
  • Cardinals vs Cubs spread: Cubs -1.5 (+136 ), Cardinals +1.5 (-165)

Cardinals vs Cubs Probable Pitchers

Matthew LiberatoreStatJavier Assad
4-5W-L6-1
0.1fWAR (FanGraphs)-0.2
5.33 / 5.53ERA / xERA4.53 / 4.85
5.10 / 4.30FIP / xFIP5.24 / 4.60
12.5K-BB%8.7
36.7GB%41.9
.329BABIP.230
98Stuff+98
101Location+104

Cardinals vs Cubs MLB Betting Preview

Action PRO projects Cardinals outfielder Alec Burleson for 1.41 hits in tonight's matchup against the Cubs, giving us a solid 8.1% edge against the market when compared to his current prop line of over/under 1.5 hits, which is enough to tag the Over with a B- grade in our system.


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Cardinals vs Cubs Pick, Betting Analysis

Burleson has already collected 92 hits this season and continues to be one of the most reliable contact bats in the Cardinals' lineup. He's cleared this line in four of his last 10 games, but this matchup sets up well for him to bounce back.

Burleson is a hitter who consistently puts the ball in play and sprays line drives to all fields, giving him multiple paths to a multi-hit game. Against a Cubs pitching staff that has shown stretches of inconsistency, that's a profile worth backing.

Pick: Alec Burleson Over 1.5 Hits (+202, bet365)


Cardinals vs Cubs Weather


Get the latest coverage on MLB Weather.
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