The Philadelphia 76ers (5-2) and Cleveland Cavaliers (4-3) will face off in the NBA tonight. Tipoff is set for 7:00 p.m. ET from Rocket Arena in Cleveland, Ohio. The game will broadcast live on FDSOH.
The Cavaliers are 10-point favorites over the Sixers on the spread (Cavaliers -10), with the over/under set at 235.5 total points. Cleveland is a -390 favorite to win outright on the moneyline, while Philadelphia is +320 to pull off the upset.
Let's get into my 76ers vs. Cavaliers predictions and NBA picks for Wednesday, November 5.
My 76ers vs Cavaliers Prediction
- 76ers vs Cavaliers picks: Cavaliers -10 / Quentin Grimes Over 3.5 Assists (+268)
My Cavaliers vs 76ers best bet is a same game parlay combining Cleveland to cover the spread and Quentin Grimes over 3.5 assists, with the best price tag currently available at bet365. But as always, make sure to find the best odds by checking our live NBA odds page.
76ers vs Cavaliers Odds
| 76ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+10 -115 | 235.5 -110o / -110u | +320 |
| Cavaliers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-10 -105 | 235.5 -110o / -110u | -390 |
76ers vs Cavaliers NBA Preview
Philadelphia comes into tonight’s matchup after a heartbreaking one-point loss to the Bulls last night.
The Sixers led most of the game by double digits, but a late three-pointer from Nikola Vucevic sealed the result.
The loss dropped Philadelphia’s record to 5–2 early in the season.
Former Kentucky standout Tyrese Maxey continues his breakout campaign, leading the NBA with 34.4 points per game.
The Cavaliers, on the other hand, entered the season as one of the favorites to contend for the Eastern Conference crown.
Cleveland is off to a 4-3 start, with two of those three losses coming against the Boston Celtics.
Veteran guard Donovan Mitchell has paced the offense, averaging 29.5 points per game.
76ers vs Cavaliers Prediction, Betting Analysis
Cavaliers -10
The Cavs are in position to roll to a comfortable victory tonight.
Philadelphia will be playing the second night of a back-to-back, meaning Joel Embiid will likely sit this one out — along with possible rest for other key players.
Cleveland should dominate the glass and the paint, and that physical advantage will make the difference in this matchup.
Quentin Grimes Over 3.5 Assists
We’re teaming up with our Action Pro Report for this prop.
The former Houston standout has averaged 5.0 assists per game early in the season and should see even more playmaking chances with Embiid sidelined.
Our Action Pro Report projects Grimes to finish with around 4.6 assists, making the over a solid value play.
Pelicans vs Clippers Best Bets, Parlay Picks
- Cavaliers -10
- Quentin Grimes Over 3.5 Assists
Parlay Payout: +268 (bet365)
Cavaliers vs 76ers Betting Trends
