LSU vs. Ole Miss Odds & Betting Predictions - September 19, 2026

LSU at Ole Miss

11:30 pm • ABC
24 - 32

LSU at Ole Miss Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
LSU
6-2
+2.5
-3-110
o58.5-110
-146
Ole Miss
5-2
u57.5
+3-108
u58.5-110
+125
location pinSaturday 11:30 p.m.
September 19, 2026
Vaught-Hemingway StadiumOxford
LSU vs. Ole Miss Expert Picks
Vegas Refund
Vegas Refund
Last 30d: 26-37-1 (-14.9u)
MISS +3-110
1u
Collin Wilson
Collin Wilson
Last 30d: 76-63-2 (+5.0u)
LSU -135
1.35u
Project LSU -6
Under 59.5-108
0.5u
Project 54
Stuck 🚨
Stuck 🚨
Last 30d: 52-65-1 (+1.0u)
MISS +3-105
0.48u
Can’t get to this number. Peaked out HFA. 🇹🇹
Mike McNamara
Mike McNamara
Last 30d: 70-57-2 (+3.8u)
MISS +3-110
0.91u
Tyler Shoemaker
Tyler Shoemaker
Last 30d: 6-8-0 (+1.3u)
LSU -2.5-110
1.1u
LSU -148
2.46u
LSU -2.5-116
0.8u
Kody Malstrom
Kody Malstrom
Last 30d: 59-46-1 (+3.4u)
LSU -3-102
0.51u
Doug Ziefel
Doug Ziefel
Last 30d: 414-387-9 (+40.1u)
LSU +137
0.36u
Boost
T.Chambliss u10.5 Rush Att-105
0.5u
D.Jones o15.5 Rush Att-120
0.5u
Neither team to 35 points +124
0.5u
K.Lacy Anytime TD Scorer Yes-175
0.5u
T.Chambliss u10.5 Rush Att-110
0.5u
Jeremiah Rose
Jeremiah Rose
Last 30d: 47-57-3 (-1.9u)
LSU +4.5 (Live)-105
0.25u
Boyd / FanDuel
S.Leavitt Anytime TD Scorer Yes (Live)+115
0.29u
LSU +10.5 (Live)-108
0.23u
Boyd / FanDuel
Ryan Minion
Ryan Minion
Last 30d: 231-233-2 (+7.7u)
LSU -2.5-120
$1.20
#Dependent on Leavitt news 🚨
LSU -150
$1.50
#Dependent on Leavitt news 🚨
OldSchool0909
Last 30d: 49-48-1 (+1.7u)
MISS +2.5-104
0.96u
Collin Whitchurch
Collin Whitchurch
Last 30d: 117-188-3 (-2.6u)
LSU -112
0.5u
S.Leavitt Anytime TD Scorer Yes+167
0.42u
Sandy Plashkes
Sandy Plashkes
Last 30d: 107-107-4 (+17.4u)
Under 59-110
1.5u
LSU +10.5 (Live)-120
1.5u
H.Fields o3.5 Recs-126
1u
Mike Calabrese
Mike Calabrese
Last 30d: 33-52-0 (-7.4u)
LSU -3-110
1.1u
Ole Miss has the better quarterback, home-field advantage, and karma on its side. What does LSU have to counter those three big checkmarks? Talent, boatloads of it. Kiffin has earned the reputation as “The Portal King,” and he’s assembled the eighth-most talented roster in the sport by closing blue-chip recruits. The aforementioned Umanmielen is an All-American talent, and he’s been unblockable through two games (5 sacks). Jordan Seaton, who was the nation’s top left tackle in the portal, has allowed just two pressures and zero sacks in 82 dropbacks this season. And then there’s the mercurial Sam Leavitt. His athleticism is undeniable, and in Kiffin’s system, he’s a dynamic rushing threat. But for every “wow” play he’s put on film this year, Bayou Bengal fans have had to deal with his questionable decision-making in equal proportion. Two red zone interceptions last week against La Tech were offset by his impressive rushing night (3 TDs). Such is the Sam Leavitt Experience™️. Leavitt has a lot in common with Louisville’s Lincoln Kienholz. Ole Miss opened against Kienholz and Louisville, and they were unable to stop him from using his legs on designed runs and extending plays when the pocket broke down. Kienholz finished with over 300 yards passing, 69 yards rushing and three total touchdowns. The Rebels blitzed Kienholz on 40% of his dropbacks and he carved them up. He connected on 66% of his pass attempts when blitzed, racking up 176 yards and a touchdown. I foresee similar success for Leavitt and this LSU offense. When Ole Miss has the football, there’s one concern that could sink the Rebels at Vaught-Hemingway Stadium, and it’s a slow start. With Kiffin and OC Charlie Weis Jr. scripting plays last season, the Rebels and Trinidad Chambliss were formidable out of the starting blocks. Seven opening-series touchdowns in the 2025 regular season showed what Kiffin and Weis Jr. brought to the table. This year it’s been a different story. Chambliss and company have scored once on four first-quarter drives before heating up later in the game. And now the Rebels are facing off against a coaching staff that helped build Chambliss into a household name. One final piece of data that is misleading is Ole Miss’ run defense. In the opener, they held Louisville to 4.2 yards per carry, but that included a 29-yard loss on a botched punt attempt. If you remove that play, Louisville ran for over five yards per carry. LSU will find a way to run the football, which will set up quick strike opportunities on playaction. If you can look past the atmosphere, the presence of Trinidad Chambliss on Ole Miss’ sideline and the public’s hatred of Lane Kiffin, the right side in this Magnolia Bowl is LSU.
LSU -9.5+210
0.5u
Adding to my position. Available at DraftKings.
Brandon Kravitz
Brandon Kravitz
Last 30d: 57-65-2 (+4.4u)
MISS +1.5-105
1u
Sam Leavitt doubtful, too good to pass up.
MISS +2.5+100
1.5u
Found a 2.5 at nearly even money on ProphetX.
Mjaybrod
Mjaybrod
Last 30d: 62-66-0 (-7.6u)
MISS u27.5-105
1u
Hit the nae nae and pray
S.Leavitt o1.5 Pass TDs-125
1u
Oh yeaaaaa
Adam Kaufman
Adam Kaufman
Last 30d: 346-314-17 (-10.0u)
LSU -2.5-122
1.22u
💰🦡 Jake
💰🦡 Jake
Last 30d: 92-108-1 (+12.7u)
MISS +135 (Live)
2.03u
Alex Hinton
Alex Hinton
Last 30d: 96-102-1 (+3.1u)
LSU +110
1u
MISS +3.5-120
0.83u
Nick Griffith
Last 30d: 55-52-0 (+6.8u)
MISS +3.5-115
1u
John Feltman
John Feltman
Last 30d: 83-53-1 (+18.6u)
Over 58.5-115
1.15u
BBOC Live!
BBOC Live!
Last 30d: 32-28-2 (+5.1u)
S.Leavitt Anytime TD Scorer Yes-110
0.91u
Under 30.5 (1H)-115
1u
MISS +3-110
0.91u

LSU vs. Ole Miss Previews & Analysis

  • Our Staff's Picks for #7 LSU vs. #8 Ole Miss article feature image

    Our Staff's Picks for #7 LSU vs. #8 Ole Miss

    Action Network Staff•
    Sep 19, 2026 UTC
  • LSU vs. Ole Miss: Kiffin's Return article feature image

    LSU vs. Ole Miss: Kiffin's Return

    Collin Wilson•
    Sep 19, 2026 UTC
  • Our 5 NCAAF Best Best for Saturday Night article feature image

    Our 5 NCAAF Best Best for Saturday Night

    Action Network Staff•
    Sep 19, 2026 UTC
  • Ryan Minion's SGP for LSU vs Ole Miss article feature image

    Ryan Minion's SGP for LSU vs Ole Miss

    Ryan Minion•
    Sep 19, 2026 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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LSU vs. Ole Miss Public Betting Percentages

Away Logo

LSU

Public

52%

Bets%

48%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Ole Miss
3-42-11-22-11-2
LSU
4-43-21-24-3N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Ole Miss
4-30-33-02-12-1
LSU
5-33-22-14-3N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Ole Miss
5-2N/AN/A3-01-2
LSU
6-2N/AN/A5-2N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 12thCHAW 41-9-45 LU 59.5-
Sep 6thLOUW 41-38-6.5 LO 54.5MISS -250
Jan 9thMIAL 27-31+3 LO 52.5MIA +142
Jan 2nd@UGAW 39-34+6 WO 53.5MISS +180
Dec 20thTULNW 41-10-16.5 WU 57.5MISS -924
Team Stats
330
Total Yards
426
70
Total Plays
73
4.714285714285714
Yards Per Play
5.835616438356165
158
YDS
363
16/27
Comps/Atts
33/48
5.851851851851852
YPA
7.5625
1/1
TDs/INTs
2/1
2/8
Sacks/Yards
2/22
172
Rush Yards
63
43
Attempts
25
4
YPC
2.52
2
TDs
2

Turnovers

0
Fumbles Lost
0
1
Interceptions
1

Efficiency

3/4 75%
Redzone
5/5 100%
9/17 0%
3rd Down
9/15 0%
2/3 0%
4th Down
1/1 0%

First Downs

19
Total
25
9
Pass
17
9
Rush
7
1
Penalty
1
7/34
Penalties/Yards
8/77

LSU vs. Ole Miss Odds Comparison

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LSU at Ole Miss Team Totals

MatchupOverUnder
LSU
6-2
N/A
N/A
Ole Miss
5-2
N/A
N/A