LSU vs. Ole Miss Odds & Betting Predictions - September 19, 2026

LSU at Ole Miss

11:30 pm • ABC
@

LSU at Ole Miss Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
LSU
2-0
+2.5
-3-110
o58.5-108
-155
Ole Miss
2-0
u57.5
+3-108
u58.5-110
+130
location pinSaturday 11:30 p.m.
September 19, 2026
Vaught-Hemingway StadiumOxford
thermometer image92°Fahrenheit
rain image0%Rain
wind image2Wind
LSU vs. Ole Miss Expert Picks
Mike McNamara
Mike McNamara
Last 30d: 54-68-1 (+1.9u)
MISS +3-110
1u
Stuck 🚨
Stuck 🚨
Last 30d: 35-35-2 (-1.9u)
MISS +3-105
0.5u
Can’t get to this number. Peaked out HFA. 🇹🇹
Brandon Kravitz
Brandon Kravitz
Last 30d: 21-28-1 (-5.5u)
MISS +2.5+100
1.5u
Found a 2.5 at nearly even money on ProphetX.
MISS +1.5-105
1.05u
Sam Leavitt doubtful, too good to pass up.
Alex Hinton
Alex Hinton
Last 30d: 52-60-2 (-5.8u)
MISS +3.5-120
1u
Doug Ziefel
Doug Ziefel
Last 30d: 249-268-11 (+8.2u)
K.Lacy Anytime TD Scorer Yes-175
0.88u
Mike Calabrese
Mike Calabrese
Last 30d: 24-25-0 (+5.8u)
LSU -9.5+210
0.5u
Adding to my position. Available at DraftKings.
Sandy Plashkes
Sandy Plashkes
Last 30d: 60-56-1 (+8.4u)
Under 59-110
1.65u
Kody Malstrom
Kody Malstrom
Last 30d: 26-15-1 (+4.7u)
LSU -3-102
0.51u
Mike Calabrese
Mike Calabrese
Last 30d: 24-25-0 (+5.8u)
LSU -3-110
1.1u
Ole Miss has the better quarterback, home-field advantage, and karma on its side. What does LSU have to counter those three big checkmarks? Talent, boatloads of it. Kiffin has earned the reputation as “The Portal King,” and he’s assembled the eighth-most talented roster in the sport by closing blue-chip recruits. The aforementioned Umanmielen is an All-American talent, and he’s been unblockable through two games (5 sacks). Jordan Seaton, who was the nation’s top left tackle in the portal, has allowed just two pressures and zero sacks in 82 dropbacks this season. And then there’s the mercurial Sam Leavitt. His athleticism is undeniable, and in Kiffin’s system, he’s a dynamic rushing threat. But for every “wow” play he’s put on film this year, Bayou Bengal fans have had to deal with his questionable decision-making in equal proportion. Two red zone interceptions last week against La Tech were offset by his impressive rushing night (3 TDs). Such is the Sam Leavitt Experience™️. Leavitt has a lot in common with Louisville’s Lincoln Kienholz. Ole Miss opened against Kienholz and Louisville, and they were unable to stop him from using his legs on designed runs and extending plays when the pocket broke down. Kienholz finished with over 300 yards passing, 69 yards rushing and three total touchdowns. The Rebels blitzed Kienholz on 40% of his dropbacks and he carved them up. He connected on 66% of his pass attempts when blitzed, racking up 176 yards and a touchdown. I foresee similar success for Leavitt and this LSU offense. When Ole Miss has the football, there’s one concern that could sink the Rebels at Vaught-Hemingway Stadium, and it’s a slow start. With Kiffin and OC Charlie Weis Jr. scripting plays last season, the Rebels and Trinidad Chambliss were formidable out of the starting blocks. Seven opening-series touchdowns in the 2025 regular season showed what Kiffin and Weis Jr. brought to the table. This year it’s been a different story. Chambliss and company have scored once on four first-quarter drives before heating up later in the game. And now the Rebels are facing off against a coaching staff that helped build Chambliss into a household name. One final piece of data that is misleading is Ole Miss’ run defense. In the opener, they held Louisville to 4.2 yards per carry, but that included a 29-yard loss on a botched punt attempt. If you remove that play, Louisville ran for over five yards per carry. LSU will find a way to run the football, which will set up quick strike opportunities on playaction. If you can look past the atmosphere, the presence of Trinidad Chambliss on Ole Miss’ sideline and the public’s hatred of Lane Kiffin, the right side in this Magnolia Bowl is LSU.
Collin Wilson
Collin Wilson
Last 30d: 44-29-0 (+10.7u)
LSU -135
1.35u
Project LSU -6
Under 59.5-108
0.54u
Project 54
Alex Hinton
Alex Hinton
Last 30d: 52-60-2 (-5.8u)
LSU +110
1u

LSU vs. Ole Miss Previews & Analysis

  • Calabrese's Best Bet for LSU vs. Ole Miss article feature image

    Calabrese's Best Bet for LSU vs. Ole Miss

    mcalabrese
    Sep 16, 2026 UTC
  • Wilson's NCAAF Week 3 Betting Card article feature image

    Wilson's NCAAF Week 3 Betting Card

    Collin Wilson
    Sep 16, 2026 UTC
See more NCAAF Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

LSU vs. Ole Miss Public Betting Percentages

Away Logo

LSU

Public

56%

Bets%

44%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Ole Miss
0-20-1N/A0-1N/A
LSU
1-11-1N/A1-1N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Ole Miss
1-10-1N/A1-0N/A
LSU
2-02-0N/A2-0N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Ole Miss
2-0N/AN/A1-0N/A
LSU
2-0N/AN/A2-0N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 12thCHAW 41-9-45 LU 59.5-
Sep 6thLOUW 41-38-6.5 LO 54.5MISS -250
Jan 9thMIAL 27-31+3 LO 52.5MIA +142
Jan 2nd@UGAW 39-34+6 WO 53.5MISS +180
Dec 20thTULNW 41-10-16.5 WU 57.5MISS -924
Team Stats
716
YDS
629
49/77
Comps/Atts
48/71
9.3
YPA
8.86
3/4
TDs/INTs
5/2
5/28
Sacks/Yards
1/6
456
Rush Yards
279
102
Attempts
65
4.47
YPC
4.29
8
TDs
5

Turnovers

Fumbles Lost
4
Interceptions
2

Efficiency

12/14 85.7%
Redzone
7/7 100%
19/33 0%
3rd Down
7/20 0%
2/2 0%
4th Down
1/2 0%

First Downs

63
Total
49
30
Pass
24
29
Rush
22
4
Penalty
3
/
Penalties/Yards
/

LSU vs. Ole Miss Odds Comparison

Right Arrow

Could not load odds

LSU at Ole Miss Team Totals

MatchupOverUnder
LSU
2-0
N/A
N/A
Ole Miss
2-0
N/A
N/A