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The Alabama Crimson Tide take on the Vanderbilt Commodores in Nashville, Tenn. Kickoff is set for 12:45 p.m. EST on SEC Network.
Alabama is favored by 15.5 points on the spread with a moneyline of -710. The total is set at 49.5 points.
Here’s my Alabama vs. Vanderbilt prediction and college football pick for Saturday, November 14, 2026.


Alabama vs Vanderbilt Prediction
- Alabama vs. Vanderbilt Pick: Vanderbilt +17.5 or Better
My Vanderbilt vs. Alabama best bet is on the Commodores. Find the best line available on our live NCAAF odds page.
Alabama vs Vanderbilt Odds
| Alabama Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-15.5 -110 | 49.5 -110o / -110u | -710 |
| Vanderbilt Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+15.5 -110 | 49.5 -110o / -110u | +520 |
- Alabama vs Vanderbilt point spread: Alabama -15.5 (-110), Vanderbilt +15.5 (-110)
- Alabama vs Vanderbilt over/under: 50.5 (-100o / -11ou)
- Alabama vs Vanderbilt moneyline: Alabama -710, Vanderbilt +520


Alabama vs Vanderbilt College Football Preview
This is a vicious situational spot for the Tide following their monumental upset win at LSU last weekend.
That all but locked up their ticket to the College Football Playoff with a very easy remaining schedule that includes Chattanooga, Auburn and this week's road date with Vandy.
Vandy also profiles as an attractive larger underdog under this staff, which will look to shorten this game at all costs by limiting the number of overall possessions.
Look for Vandy to play slower and to take all of the underneath stuff that Kane Wommack's defense will allow. We've also seen Alabama struggle as a larger road favorite under Kalen DeBoer in recent seasons.
The Commodore defense will be overmatched from a talent standpoint, but they do a pretty decent job of limiting explosive passing plays and bringing pressure, which are both required boxes you must check to slow down Alabama's potent offense.
Plus, star quarterback Keelon Russell is dealing with a bit of an ankle injury, so he may not run as frequently in this particular game. You could also see a quicker hook with a bigger lead, which could open up the backdoor if needed.
Additionally, the Alabama staff has also talked about how they must improve their rushing attack, so I wouldn't be surprised if the Tide go a bit heavier with the run game in Nashville, which would obviously help shorten the game and give Vandy a better shot at keeping this within the number.
It's been a disappointing season for Vanderbilt, but this can serve as a bit of a Super Bowl (expect a trick play or two), while I'm not sold that we get a fully locked-in Alabama squad following that win at LSU.
Plus, I imagine we might eventually see some negative turnover regression for Alabama. The Tide lead the nation with an absurd +52 net EPA from turnovers. For reference, Louisiana Tech ranks second at +41, and Vanderbilt sits outside the top 90 at -7.5.
Pick: Vanderbilt +17.5 or Better














