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The Ole Miss Rebels take on the Oklahoma Sooners in Norman, Oklahoma. Kickoff is set for 4:15 p.m. EST on SEC Network.
Ole Miss is favored by 1.5 points on the spread with a moneyline of -104. The total is set at 49.5 points.
Here’s my Ole Miss vs. Oklahoma prediction and college football pick for Saturday, November 14, 2026.
Ole Miss vs Oklahoma Prediction
- Ole Miss vs. Oklahoma Pick: Oklahoma -1 or Better
My Oklahoma vs. Ole Miss best bet is on the Sooners. Find the best line available on our live NCAAF odds page.
Ole Miss vs Oklahoma Odds
| Ole Miss Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +110 | 49.5 -110o / -110u | -104 |
| Oklahoma Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -130 | 49.5 -110o / -110u | -115 |
- Ole Miss vs Oklahoma point spread: Ole Miss -1.5 (+110), Oklahoma +1.5 (-130)
- Ole Miss vs Oklahoma over/under: 49.5 (-110o / -110u)
- Ole Miss vs Oklahoma moneyline: Ole Miss -104, Oklahoma -115
Ole Miss vs Oklahoma College Football Preview
I couldn't have been more wrong about last week's playoff rematch between Ole Miss and Georgia. The Rebels got absolutely stomped from start to finish in every facet.
Now, with three losses under their belts and only games against Mississippi State and Wofford remaining over the final two weeks, I don't see a path to the College Football Playoff, which the Ole Miss locker room is likely fully aware of.
There's a reason you're hearing about season-ending injuries and the portal already in Oxford. Do they show up this week in Norman? It's certainly a question worth posing for a team that had national title aspirations.
Even if Ole Miss is fully locked in during practice all week and shows up ready to roll on Saturday, I still would feel confident holding a Sooners ticket.
Let's start with injuries, where these two teams are headed in opposite directions. The Rebels recently learned star running back Kewan Lacy will shut it down for the remainder of the season.
Plus, they will have to make do this week without their best offensive lineman in Patrick Kutas and leading tackler in linebacker Keaton Thomas.
Meanwhile, the Oklahoma offensive line is finally getting back to full strength.
The biggest addition was getting starting left tackle Michael Fasusi back a few weeks ago. There was previously a massive void at left tackle, which has since been filled by the former five-star who finally looked 100% healthy last week at Florida.
Not only will pass protection improve immensely, but the running game should continue to look more competent the rest of the season, especially against an Ole Miss defense that has plenty of holes against the run and pass.
Last week also marked the debut of Oklahoma's new play-caller, Jason Witten. I thought he did a fantastic job with play sequencing, and the entire operation just looked cleaner.
Most importantly, Oklahoma didn't have any turnovers, which have absolutely killed them all season. Witten also unleashed John Mateer with a higher rate of designed runs.
It also helps that Mateer is finally playing with confidence. Earlier in the season, he could barely scramble without literally dropping the ball and was extremely hesitant to fire on his reads. It was as if he almost had the quarterback version of the yips.
With that said, it's not like this offense is going to turn into the 1999 Rams. This is still a team that's led by an elite defense that should get constant pressure on Trinidad Chambliss, especially without Kutas and a backfield that struggles in picking up blitzes.
Chambliss has really struggled against the last two top-tier defenses he faced in Texas and Georgia. This is just not the same offense as last year. Not only is Lacy done for the year, but there's a new play-caller, and the pass-catchers aren't as talented.
As a result, Chambliss' efficiency numbers have fallen precipitously when under pressure. That could spell doom against a Brent Venables stop unit that generates pressure at one of the highest rates in the country.
From a regression standpoint, don't be surprised if Oklahoma falls on a key fumble or two. The Sooners have the lowest fumble recovery rate in the country at 23%, while the Rebels rank 20th in that department at nearly 80%.
This is not my typical buy-low / sell-high spot, as Ole Miss got blown out last week, while Oklahoma pulled off a road upset.
However, I still think this sets up well for the Sooners, who are trending up offensively with a defense that should give Chambliss fits. And I do question whether or not we get a fully locked-in Rebels bunch this week.
Boomer.
Pick: Oklahoma -1 or Better

















