49ers vs. Buccaneers Odds & Betting Predictions - October 12, 2025

49ers at Buccaneers

5:00 pm • CBS

San Francisco 49ers

@

Tampa Bay Buccaneers

MatchupOpenSpreadTotalMoneyline
49ers 3-0	N/A	N/A	N/A
Buccaneers 3-0	N/A	N/A	N/A

location pin

Sunday 5:00 p.m.

October 12, 2025

Raymond James StadiumTampa

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NFL Public Betting

Buccaneers are 3-0 in their last 5 games.
Buccaneers are 2-1 in their last 5 games against the spread
Buccaneers are 2-0 in their road games against the spread
The totals have gone OVER in 1 of Buccaneers' last 3 games
The totals have gone OVER in 1 of Buccaneers' 1 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Buccaneers	2-1	0-1	2-0	1-1	1-0
49ers	2-1	0-1	2-0	2-1	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Buccaneers	1-2	1-0	0-2	1-1	0-1
49ers	1-2	0-1	1-1	1-2	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Buccaneers	3-0	N/A	N/A	2-0	1-0
49ers	3-0	N/A	N/A	3-0	N/A

date	opponent	score	spread	over/under	moneyline
Sep 21st	NYJ	W 29-27	-6.5 L	O 43.5	TB -320
Sep 15th	@HOU	W 20-19	+2.5 W	U 42.5	TB +130
Sep 7th	@ATL	W 23-20	-1.5 W	U 47.5	TB -110
Aug 23rd	BUF	L 19-23	+1.5 L	O 37.5	BUF +105
Aug 16th	@PIT	W 17-14	-1.5 W	U 36.5	TB -120

Mike Evans
WR
Evans is out with hamstring
Out

Chris Godwin
WR
Godwin is questionable with ankle
Questionable
Tristan Wirfs
T
Wirfs is out with knee
Out
Christian Izien
S
Izien is out with oblique
Out
Benjamin Morrison
CB
Morrison is out with quad
Out

George Kittle
TE
Kittle is out with hamstring
Out
Brandon Aiyuk
WR
Aiyuk is out with knee
Out
Jauan Jennings
WR
Jennings is questionable with ankle
Questionable
Brock Purdy
QB
Purdy is questionable with toe
Questionable
Jacob Cowing
WR
Cowing is out with hamstring
Out
Jordan Watkins
WR
Watkins is doubtful with ankle
Doubtful
Jordan James
RB
James is doubtful with finger
Doubtful

See more NFL Injuries

passing yards
Baker Mayfield
615
pyds
passing touchdowns
Baker Mayfield
6
ptd
rushing yards
Bucky Irving
174
ryds
rushing touchdowns
Rachaad White
1
rtd

	Starter	2ND	3RD	4TH
QB	Baker Mayfield	Teddy Bridgewater	Connor Bazelak
RB	Bucky Irving	Rachaad White	Sean Tucker	Josh Williams
WR	Chris Godwin	Emeka Egbuka	Sterling Shepard	Kameron Johnson
TE	Cade Otton	Payne Durham	Devin Culp	Ko Kieft	Tanner Taula
LT	Tristan Wirfs	Charlie Heck	Benjamin Chukwuma	Lorenz Metz
LG	Ben Bredeson	Elijah Klein
C	Graham Barton	Ben Scott
RG	Cody Mauch	Luke Haggard	Sua Opeta
RT	Luke Goedeke	Michael Jordan	Tyler McLellan
LDE	Logan Hall	Elijah Roberts
RDE	Calijah Kancey	C.J. Brewer	Adam Gotsis
LCB	Zyon McCollum	Josh Hayes
SS	Tykee Smith	Kaevon Merriweather	Rashad Wisdom
FS	Antoine Winfield
RCB	Jamel Dean	Benjamin Morrison	Bryce Hall
P	Riley Dixon
H	Riley Dixon
PR	Tez Johnson	Garrett Greene
KR	Sean Tucker	Garrett Greene
LS	Evan Deckers
NB	Jacob Parrish	Christian Izien	Kindle Vildor
ROLB	Yaya Diaby	Chris Braswell
RILB	SirVocea Dennis	John Bullock
NT	Vita Vea	Greg Gaines	Nash Hutmacher
LILB	Lavonte David	Deion Jones	Nick Jackson
LOLB	Haason Reddick	Anthony Nelson	Markees Watts
K	Chase McLaughlin
RWR	Jalen McMillan	Tez Johnson	Garrett Greene
LWR	Mike Evans	Ryan Miller	Dennis Houston

Total

Passing

814

YDS

575

79/115

Comps/Atts

61/99

7.304

YPA

6.212

6/3

TDs/INTs

6/0

5/26

Sacks/Yards

6/40

Rushing

269

Rush Yards

392

82

Attempts

87

3.28

YPC

4.506

0

TDs

1

Turnovers

Fumbles Lost

3

Interceptions

0

Efficiency

5/11 45.46%

Redzone

4/9 44.44%

17/39 0%

3rd Down

17/41 0%

3/4 0%

4th Down

2/2 0%

First Downs

66

Total

60

44

Pass

34

16

Rush

18

6

Penalty

8

Misc

/

Penalties/Yards

/

Possession

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MatchupOverUnder
49ers 3-0	N/A	N/A
Buccaneers 3-0	N/A	N/A