Falcons vs. Panthers Odds & Betting Predictions - September 21, 2025

Falcons at Panthers

5:00 pm • FOX
0 - 30

Falcons at Panthers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Falcons
1-2
-2.5
-4.5-110
o44-110
-225
Panthers
1-2
u44.5
+4.5-110
u44-110
+185
location pinSunday 5:00 p.m.
September 21, 2025
Bank of America StadiumCharlotte
Falcons vs. Panthers Expert Picks
The Degenerates
The Degenerates
Last 30d: 71-76-2 (-12.8u)
B.Robinson o108.5 Rush + Rec Yds (Live)-115
1u
Vegas Refund
Vegas Refund
Last 30d: 33-29-2 (+0.9u)
CAR +5.5-112
1u
Derek Carty
Derek Carty
Last 30d: 11-15-0 (-1.9u)
D.Moore u16.5 Rec Yds-110
1u
There may be some value on the receiving yards prop for David Moore. THE BLITZ is projecting him to record 13.34 receiving yards, and the oddsmakers are implying 22.99. The model believes there is a 71% chance he records fewer than 16.5 receiving yards. If you can get the under at -115 or better, there is some great value here. Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Chris Raybon
Chris Raybon
Last 30d: 20-17-1 (+14.0u)
B.Tremayne Anytime TD Scorer Yes+1000
0.5u
WR3 w/ Leggette out. 6’4” RZ target
Babs .
Babs .
Last 30d: 78-63-1 (+12.8u)
Over 20.5 (1H)-110
0.66u
Firefighter Bets
Firefighter Bets
Last 30d: 172-160-0 (+3.2u)
H.Renfrow o35.5 Rec Yds+115
1u
Picks Office
Picks Office
Last 30d: 62-87-4 (-21.4u)
ATL -5.5+105
1u
Firefighter Bets
Firefighter Bets
Last 30d: 172-160-0 (+3.2u)
K.Pitts o39.5 Rec Yds-125
1u
Shady Biev
Shady Biev
Last 30d: 46-54-1 (-4.8u)
CAR +5-113
1.5u
Matthew Freedman
Matthew Freedman
Last 30d: 29-36-0 (-5.8u)
B.Young o0.5 Int-137
0.69u
Projection: -183. For more, check out the Fantasy Life player projections.
Gilles Gallant
Gilles Gallant
Last 30d: 17-50-0 (-4.2u)
H.Renfrow Anytime TD Scorer Yes+400
0.5u
Moneyline Hacks
Moneyline Hacks
Last 30d: 110-127-8 (+45.5u)
Under 44-110
0.91u
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Sean Koerner
Sean Koerner
Last 30d: 24-31-0 (-2.1u)
B.Young u211.5 Pass Yds-113
0.5u
This feels like a sell-high spot after Young threw for 328 yards last week, with 217 of those coming in the second half during a pass-heavy comeback script. That’s been the Panthers’ theme so far, trailing for a league-high 52 minutes per game. They’re 5-point underdogs again here, but there’s at least a chance they keep this one closer (or even play with a rare lead) which would be the best outcome for this under. If they cover, it’s likely because the run game finally showed up. Even if they fall behind, I don’t expect the same level of efficiency against a Falcons defense that looks much improved. Losing AJ Terrell hurts, but Atlanta’s upgraded pass rush with two first-round picks has made this a tough matchup for QBs. Young is also unlikely to benefit from the extreme play volume Carolina has seen so far, as they’re averaging 10 more plays per game than last year. Some regression there should pull back his yardage totals. Overall, this is simply a spot to fade last week’s spike game. I project Young closer to 197.5 yards, so we’ve got enough value to grab the under.
Allan Lem
Allan Lem
Last 30d: 117-104-5 (+1.1u)
J.Sanders u2.5 Recs+125
0.5u
Tailing @nick_giffen
Nick Giffen
Nick Giffen
Last 30d: 38-98-0 (+11.2u)
J.Sanders u2.5 Recs+125
1.25u
Ja'Tavion Sanders under 2.5 rec (+125 Bet365) Both last year and this year so far, Sanders' target share and targets per route run fall off a cliff when he faces single-high coverage as opposed to two-high coverage 12.3% vs. 5.3% target share and 0.21 to 0.09 TPRR last year (two vs. single) 16.3% vs. 9.8% target share and 0.22 vs 0.14 TPRR this year (two vs. single) The targets are also longer, with an average depth of 9.8 (single) to 8.1 (two) this year and 6.6 vs 5.8 last year, meaning catch rates will be lower on those targets I say all this because the Falcons have played single-high coverage at the 3rd highest rate so far this year, after CAR faced ARI and JAX who have both bottom-10 in single-high rates CAR hopefully is more competitive in this game, as they've played 142 of 146 offensive snaps while trailing, leading to 90 Bryce Young pass attempts through two games. Bryce should be handing it off more frequently this weekend. Through two weeks, ATL has conceded the fewest targets to TEs (6) while allowing just 1 catch. Projecting 2.45 with 55.5% chance of staying under, making +125 solid value
💰🦡 Jake
💰🦡 Jake
Last 30d: 95-108-7 (+34.5u)
B.Robinson o17.5 Rush Att-120
1.2u
Brandon Anderson
Brandon Anderson
Last 30d: 16-81-0 (-24.6u)
CAR +6-110
0.91u
Oh you better believe it's going to feel gross betting some of these Kitchen Sink teams. And that's exactly the point — sometimes as a bettor, you have to make a bet that doesn't make any sense, sometimes even to yourself. I can make a much easier case for the Falcons. Carolina's lone real offensive strength was its line, now missing Austin Corbett and Robert Hunt with Ikem Ekwonu also banged up, and Atlanta's improved pass rush looked fearsome against an equally-injured Minnesota line on Sunday night. The Panthers offense ranks near worst in many offensive metrics, and its defense was just as bad last year, especially against the run — dangerous against Atlanta. That's why this line rose all week, from Falcons -2.5 on Sunday morning all the way to -6.5 at one point. That's a huge swing — across the key number of three and another at six — and it's too far and represents overconfidence in this young Atlanta team. Even after sweeping upgrades to the Falcons after an impressive win, I still have this number pretty close to where it was Sunday, about -3. Are we sure the Falcons have an elite defense, just like that? Atlanta ranks second by Defensive DVOA through two games, but it would be stunning to see the Falcons finish anywhere near that high. This is a team starting third- and fourth-round rookies in its secondary, which will be without top corner A.J. Terrell this week. That could be a problem against Panthers rookie WR Tet McMillan who already looks like a star after hitting 100 yards last week. It's also a good reminder to zoom out past these two weeks. Division rivalries are tough, and these teams have split the season series five consecutive seasons, with seven of those 10 games finishing within one score. That would likely do the trick for a cover here! But look, more than anything else, this is just trusting the Week 3 Kitchen Sink trends and betting the number. This is my highest-rated Kitchen Sink spot of 2025 because of so many sub-trends within the trend. Kitchen Sink teams in division games are 75% ATS, and they're also 75% ATS with a total under 44 and 71% ATS if the opponent has scored under 27 both its games. Atlanta's offense isn't putting up big numbers, and lower-scoring games are easier to cover, even through the backdoor. Kitchen Sink teams are also 70% ATS against 1-1 opponents and 68% for public sides, with the Panthers getting about two-thirds of the bets. I don't like backing the Panthers either. It's gross! And that's exactly why we have to do it.
Action Pod NFL Picks
Action Pod NFL Picks
Last 30d: 28-80-0 (-25.0u)
CAR +6-110
0.91u
Grant Neiffer
Grant Neiffer
Last 30d: 42-145-11 (+1.9u)
K.Pitts Anytime TD Scorer Yes+290
0.5u
Cam Is Money
Cam Is Money
Last 30d: 50-57-1 (-9.6u)
CAR +5.5-115
0.87u
Kenny Ducey
Kenny Ducey
Last 30d: 27-21-1 (+4.7u)
ATL -5.5-108
1.08u
CeeJ Sports
CeeJ Sports
Last 30d: 10-6-0 (+1.9u)
B.Robinson o75.5 Rush Yds-110
1.1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 110-127-8 (+45.5u)
X.Legette u30.5 Rec Yds-110
1u
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Boomer Betz
Boomer Betz
Last 30d: 121-115-1 (+7.5u)
CAR +5.5-109
0.92u
Bet105
Kyle Murray
Kyle Murray
Last 30d: 47-48-3 (+2.4u)
ATL -3.5-105
1.05u
Matt Moore
Matt Moore
Last 30d: 10-13-1 (-3.8u)
CAR +3.5-105
1.05u
FTN Fantasy
FTN Fantasy
Last 30d: 70-91-0 (-28.9u)
CAR +3.5-105
0.95u

Falcons vs. Panthers Previews & Analysis

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Falcons vs. Panthers Props

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Falcons vs. Panthers Public Betting Percentages

Away Logo

Falcons

Public

43%

Bets%

57%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Panthers
2-11-01-1N/A2-1
Falcons
1-20-11-10-11-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Panthers
1-20-11-1N/A1-2
Falcons
0-30-10-20-10-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Panthers
1-2N/AN/AN/A1-2
Falcons
1-2N/AN/A0-11-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 14th@ARIL 22-27+7 WO 45.5ARI +265
Sep 7th@JACL 10-26+4.5 LU 45.5JAC +184
Aug 21stPITL 10-19+6.5 LU 34.5PIT +235
Aug 16th@HOUL 3-20+3 LU 38.5HOU +130
Aug 8thCLEL 10-30-5.5 LO 33.5CLE -250

Falcons vs. Panthers Injury Updates

Falcons Injuries

  • Jamal Agnew
    WR

    Agnew is out with groin

    Out

  • DeMarcco Hellams
    S

    Hellams is out with hamstring

    Out

  • Casey Washington
    WR

    Washington is questionable with concussion

    Questionable

  • Jack Nelson
    OL

    Nelson is out with calf

    Out

Panthers Injuries

  • Ikem Ekwonu
    T

    Ekwonu is doubtful with illness

    Doubtful

  • Damarri Mathis
    CB

    Mathis is out with knee

    Out

  • Xavier Legette
    WR

    Legette is questionable with hamstring

    Questionable

  • Ja'Tavion Sanders
    TE

    Sanders is out with ankle

    Out

  • Jalen Coker
    WR

    Coker is out with quad

    Out

Team Stats
332
Total Yards
224
66
Total Plays
55
5
Yards Per Play
4.1
201
YDS
121
23/43
Comps/Atts
16/24
4.674
YPA
4.56
0/2
TDs/INTs
0/0
0/0
Sacks/Yards
1/7
131
Rush Yards
110
23
Attempts
30
5.696
YPC
3.667
0
TDs
2
1
Fumbles Lost
1
2
Interceptions
0

Efficiency

0/0 0%
Redzone
2/3 66.67%
5/13 0%
3rd Down
3/11 0%
0/3 0%
4th Down
2/2 0%

First Downs

17
Total
15
11
Pass
7
6
Rush
7
0
Penalty
1
3/23
Penalties/Yards
6/55
28:02
Possession
31:58

Falcons vs. Panthers Odds Comparison

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Falcons at Panthers Team Totals

MatchupOverUnder
Falcons
1-2
o24.5-105
u24.5-117
Panthers
1-2
o19.5-116
u19.5-105