Bengals vs. Bills Odds, Picks & More

Bengals at Bills Betting Odds

• Odds: Bills -6
• Total: 44
• Time: 1 p.m. ET
• TV Channel: CBS

Odds above as of Sunday morning and via PointsBet, where Action Network users can exclusively bet every NFL spread this season at reduced juice (-105).

Sean Koerner compares his projected spread and total to the market to identify any potential value, while our staff reveals how they’re betting this game.

Sean Koerner’s Projected Odds

• Projected Spread: Bills -6.5
• Projected Total: 42

The Bills are correctly favored here.

The total opened 1.5 points below my projection but has been bet up to two points higher than my projection.

I don’t think the market has reached its apex as of early Sunday, as it looks like this number could go up to 44.5. Forty-four is a fairly key number, so it’s worth waiting to see if we can get the hook with 44.5. Once it reaches that number, I think the sharps will come in and quickly send it back down to 44 — or even 43.5 — before kickoff. — Sean Koerner

Expert Pick

Mike Randle: Bills -6

It’s time to believe in Buffalo head coach Sean McDermott.

The Bills have started the season with two consecutive road wins for the first time in franchise history. Buffalo last started the season 2-0 in 2014, with wins at the Bears and home against the Dolphins.

Buffalo has one of the best defensive units in the NFL, particularly against the pass. The Bills ranked second in the league in Football Outsiders’ pass defense DVOA in 2018, which will cause problems for a Cincinnati offense still without All-Pro wideout A.J. Green. Bengals quarterback Andy Dalton is second among all quarterbacks with 729 passing yards, but that has translated to just 37 total points.

Bengals lead running back Joe Mixon played through an ankle injury in Week 2 and was largely ineffective (11 rushes for 17 yards). Establishing the run game is essential for a Bengals offensive line that has allowed nine sacks over the first two games.

Cincinnati’s defense was equally atrocious in Week 2, allowing an incredible 259 rushing yards and three passing touchdowns to quarterback Jimmy Garoppolo.

Look for the Bills to roll in their home opener to a comfortable win. I would take this line up to Buffalo -8.