The Houston Astros host the Arizona Diamondbacks on September 4, 2026. First pitch from Daikin Park is scheduled for 8:10 p.m. ET. The game will be broadcast on ARID.
The Astros are favored by -136 on the moneyline and by -1.5 on the run line. The Diamondbacks are +116 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find our MLB picks and Diamondbacks vs Astros prediction below, as well as probable pitchers, weather report, and more.
Diamondbacks vs Astros Prediction
- Diamondbacks vs Astros Pick: Diamondbacks ML (+116)
Our Diamondbacks vs Astros best bet is on Arizona to win outright. Make sure to find the best odds by checking our live MLB odds page.
Diamondbacks vs Astros Odds
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -184 | 8.5 -124o / 102u | +116 |
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +152 | 8.5 -124o / 102u | -136 |
- Diamondbacks vs Astros moneyline: Diamondbacks +116, Astros -136
- Diamondbacks vs Astros over/under: 8.5 (-124o / +102u)
- Diamondbacks vs Astros spread: Diamondbacks +1.5 (-184), Astros -1.5 (+152)
Diamondbacks vs Astros Probable Pitchers
| Merrill Kelly (RHP, ARI) | Stat | Cristian Javier (RHP, HOU) |
|---|---|---|
| 9-12 | W-L | 1-5 |
| -0.4 | fWAR (FanGraphs) | 0.1 |
| 5.08 / 6.93 | ERA / xERA | 6.45 / 5.17 |
| 5.56 / 4.99 | FIP / xFIP | 4.95 / 5.02 |
| 5.0 | K-BB% | 11.3 |
| 40.8 | GB% | 24.3 |
| .280 | BABIP | .346 |
| 89 | Stuff+ | 100 |
| 101 | Location+ | 101 |
Diamondbacks vs Astros MLB Betting Preview
Sean Zerillo's projections show solid value on the Diamondbacks moneyline tonight against the Astros.
If you want to dive deeper into this matchup, it'd be wise to check out BARTOLO, Zerillo's new PRO baseball tool that gives you access to all the input data he uses to project games every day.
Diamondbacks vs Astros Pick, Betting Analysis
BARTOLO projects Arizona for 4.59 runs and Houston for 4.28, giving us a 5.1% edge on the moneyline for the visitors.
The Diamondbacks have been fairly decent on the road with a 33-36 record, while the Astros are 36-36 at home.
Tonight's starting pitchers are way down in Zerillo's SP rankings, with Merrill Kelly in the 190th spot and Cristian Javier at 169.
Both bullpens are efficient and ranked 10th (Arizona) and 11th (Houston), but BARTOLO's projections give the edge to the Snakes' lineup, which gets excellent grades for contact and defense, as you can see below.
Over the past 30 days, Arizona ranks 15th in wRC+ in the majors with a rating of 100, and the Astros are 28th with an 82 rating.
At plus money, the Diamondbacks are the pick to make.
Pick: Diamondbacks ML (+116, FanDuel)
