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White Sox vs Twins Prediction, Pick, MLB Odds for Friday, August 28

White Sox vs Twins Prediction, Pick, MLB Odds for Friday, August 28 article feature image
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Bruce Kluckhohn-Imagn Images. Pictured: Twins catcher Ryan Jeffers

The Minnesota Twins host the Chicago White Sox on August 28, 2026. First pitch from Target Field is scheduled for 8:10 p.m. ET. The game will be broadcast on MNNT.

The White Sox are favored by -118 on the moneyline and are +1.5 on the run line. The Twins are +100 on the moneyline and -1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and White Sox vs Twins prediction below, as well as probable pitchers, weather report, and more.


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White Sox vs Twins Prediction

  • White Sox vs Twins Pick: Twins ML (-118)

My White Sox vs Twins best bet is on Minnesota to win outright. Make sure to find the best odds by checking our live MLB odds page.


White Sox vs Twins Odds

White Sox Logo
Friday, Aug 28
8:10 p.m. ET
MNNT
Twins Logo
White Sox Odds
SpreadTotalMoneyline
-1.5
+168
8.5
-124o / 102u
+100
Twins Odds
SpreadTotalMoneyline
+1.5
-205
8.5
-124o / 102u
-118
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • White Sox vs Twins moneyline: White Sox +100, Twins -118
  • White Sox vs Twins over/under: 8.5 (-124o / +102u)
  • White Sox vs Twins spread: White Sox -1.5 (+168), Twins +1.5 (-205)

White Sox vs Twins Probable Pitchers

Luis Castillo (RHP, CHW)StatDean Kremer (RHP, MIN)
4-10W-L2-4
0.6fWAR (FanGraphs)0.1
5.19 / 4.92ERA / xERA5.22 / 4.28
4.69 / 4.34FIP / xFIP5.18 / 3.85
13.0K-BB%16.3
37.5GB%37.5
.305BABIP.243
96Stuff+91
108Location+93

White Sox vs Twins MLB Betting Preview, Prediction

Luis Castillo was excellent in his June 12 start against the Cincinnati Reds. He posted 10 Ks in seven innings pitched, allowing one hit, two walks, and no earned runs. This start looked like a new era for the former ace, but it may have just been a blip against the league's worst offense against RHP.

In his two starts since this incredible outing, Castillo has allowed seven ER, 16 hits, and two walks in 7 1/3 IP. He struck out four total batters in this span against the Mets and Cubs.

Castillo now faces a Twins offense that ranks sixth against RHP this season (105 wRC+). Minnesota may be without star OF Byron Buxton, but he is ice-cold since returning from the IL on August 13 (61 wRC+).

The Twins have a solid lineup throughout the order and can punish Castillo's mistakes. They're also starting reformed SP Dean Kremer.

Kremer was a trade deadline addition who has improved since the deal to Minnesota. He has a 3.18 ERA, backed by a 3.30 xERA and 3.98 xFIP in four starts with the Twins.

While Kremer has flashed excellence for spurts before, he is pitching with a notable change in groundball rate from 33% with the Orioles to 45.6% with the Twins.

If he can sustain it, 45.6% would be a career-high GB% for Kremer. He finished a season above 40% once (2024).

The Chicago White Sox offense is the best in baseball through the past two weeks, but they are getting no help from star hitters Colson Montgomery and Munetaka Murakami. Tristan Peters' fluky output is carrying them this week.

Chicago's offense is also much better at home (110 wRC+) than on the road (101). The same is true for the Twins, giving them a slight advantage.

Both teams have fresh bullpens, but the White Sox will likely have to call upon theirs sooner.

Pick: Twins ML (-118, FanDuel)


White Sox vs Twins Weather


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About the Author
Kevork MahserejianVerified Action Expert

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