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Dodgers vs Reds Prediction, Pick, MLB Odds for Tuesday, September 15

Dodgers vs Reds Prediction, Pick, MLB Odds for Tuesday, September 15 article feature image
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Pictured: Los Angeles Dodgers pitcher Yoshinobu Yamamoto. (Credit: Kiyoshi Mio-Imagn Images)

The Cincinnati Reds host the Los Angeles Dodgers on September 15, 2026. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on CINR.

The Dodgers are favored by -240 on the moneyline and by -1.5 on the run line. The Reds are +198 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Dodgers vs Reds prediction below, as well as probable pitchers, weather report, and more.


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Dodgers vs Reds Prediction

  • Dodgers vs Reds Pick: Under 8.5 (-105)

My Dodgers vs Reds best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page, and download the Action Network app for more picks and analysis.


Dodgers vs Reds Odds

Dodgers Logo
Tuesday, Sep 15
6:40 p.m. ET
CINR
Reds Logo
Dodgers Odds
SpreadTotalMoneyline
-1.5
-144
8.5
-115o / -105u
-240
Reds Odds
SpreadTotalMoneyline
+1.5
+120
8.5
-115o / -105u
+198
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Dodgers vs Reds moneyline: Dodgers -240, Reds +198
  • Dodgers vs Reds over/under: 8.5 (-115o / -105u)
  • Dodgers vs Reds spread: Dodgers -1.5 (-144), Reds +1.5 (+120)

Dodgers vs Reds Probable Pitchers

Yoshinobu Yamamoto (RHP, LAD)StatRhett Lowder (RHP, CIN)
13-8W-L6-10
4.3fWAR (FanGraphs)1.2
2.62/3.05ERA / xERA5.81/5.35
3.34/3.24FIP / xFIP4.71/4.81
20.1%K-BB%8.3%
48.4%GB%40.8%
.222BABIP.308
102Stuff+87
107Location+103

Dodgers vs Reds MLB Betting Preview

Sean Zerillo's projections show solid value on the total for this Dodgers vs. Reds matchup, with a 7.1% edge on the under.

If you want to dive deeper into this matchup, it'd be wise to check out BARTOLO, Zerillo's new PRO baseball tool that gives you access to all the input data he uses to project games every day.


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Dodgers vs Reds Pick, Betting Analysis

BARTOLO projects the Dodgers for 4.57 runs and the Reds for 3.21 tonight, which would bring the total under the line (8.5).

The starting pitching matchup is where this game is set up. Los Angeles sends Yoshinobu Yamamoto to the mound (13-8, 2.62 ERA, 171 SO), giving them a massive edge over Cincinnati's Rhett Lowder (6-10, 5.81 ERA, 94 SO).

Beyond the rotation, Los Angeles holds a clear secondary advantage in the late innings. BARTOLO rates the Dodgers' bullpen as one of the best in baseball, taking a top-tier spot in the rankings.

It's going to be a tough assignment for a Cincinnati lineup that faces high-end right-handed pitching, making quality run production hard to come by against an ace like Yamamoto.

While the Dodgers boast a potent offense capable of doing damage against Lowder, Los Angeles' pitching and bullpen control should keep the Reds contained enough to keep this total under 8.5.

Let's go with BARTOLO's projection and pick the under tonight.

Pick: Under 8.5 (-105)


Dodgers vs Reds Weather


Get the latest coverage on MLB Weather.


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