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Phillies vs Mariners Prediction, Pick, MLB Odds for Wednesday, August 26

Phillies vs Mariners Prediction, Pick, MLB Odds for Wednesday, August 26 article feature image
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Jordan Johnson-Imagn Images. Pictured: Phillies SP Jesus Luzardo

The Seattle Mariners host the Philadelphia Phillies on August 26, 2026. First pitch from T-Mobile Park is scheduled for 4:10 p.m. ET. The game will be broadcast on SEAM.

The Phillies are favored by -125 on the moneyline and by -1.5 on the run line. The Mariners are +115 on the moneyline and +1.5 on the run line. The total is set at 6.5 runs.

Find our MLB picks and Phillies vs Mariners prediction below, as well as probable pitchers, weather report, and more.


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Phillies vs Mariners Prediction

  • Phillies vs Mariners Pick: Jesus Luzardo Over 7.5 Strikeouts (+125)

Our Phillies vs Mariners best bet is on the over on Jesus Luzardo's strikeouts prop. Make sure to find the best odds by checking our live MLB odds page.


Phillies vs Mariners Odds

Phillies Logo
Wednesday, Aug 26
4:10 p.m. ET
SEAM
Mariners Logo
Phillies Odds
SpreadTotalMoneyline
-1.5
+140
6.5
-130o / 110u
-125
Mariners Odds
SpreadTotalMoneyline
+1.5
-165
6.5
-130o / 110u
+115
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Phillies vs Mariners moneyline: Phillies -125, Mariners +115
  • Phillies vs Mariners over/under: 6.5 (-130o / -110u)
  • Phillies vs Mariners spread: Phillies -1.5 (+140), Mariners +1.5 (-165)

Phillies vs Mariners Probable Pitchers

Jesus Luzardo (LHP, PHI)StatBryan Woo (RHP, SEA)
11-5W-L9-8
4.6fWAR (FanGraphs)3.1
3.35 / 2.88ERA / xERA4.10 / 3.56
2.84 / 2.92FIP / xFIP3.29 / 3.71
22.8K-BB%19.2
48.2GB%36.8
.312BABIP.283
111Stuff+109
103Location+108

Phillies vs Mariners MLB Betting Preview, Prediction

Action PRO projects Phillies starter Jesus Luzardo for 7.84 strikeouts against the Mariners this afternoon, giving us a solid 8.0% edge against the market when compared to his current prop line of over/under 7.5, which is good enough to tag the over with a B- grade in our system.

Luzardo is fanning batters at a record clip in his career, with an extraordinary 11.19 Ks per nine innings. He only had a higher rate (12.00) in his debut season in 2019, when he pitched just 12 innings.

He has surpassed this line in his past three starts, with totals of 12, 9, and 9 strikeouts in those games.

Luzardo will face one of the worst lineups in wRC+ against southpaws, as the Mariners rank 26th with an 89 rating. They're also in the bottom 10 in MLB (22nd spot) in strikeout percentage vs. lefties with 24.3%.

At plus money, let's back him tonight to keep punching out in Seattle.

Pick: Jesus Luzardo Over 7.5 Strikeouts (+125, bet365)


Phillies vs Mariners Weather


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