The Cincinnati Reds host the St. Louis Cardinals on August 17, 2026. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on CARD.
The Cardinals are favored by -118 on the moneyline and by -1.5 on the run line. The Reds are +110 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Cardinals vs Reds prediction below, as well as probable pitchers, weather report, and more.
Cardinals vs Reds Prediction
- Cardinals vs Reds Pick: Rhett Lowder Under 4.5 Strikeouts (-156, FanDuel)
My Cardinals vs Reds best bet is on Lowder to record under 4.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Cardinals vs Reds Odds
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +130 | 9 -115o / -105u | -118 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -156 | 9 -115o / -105u | +110 |
- Cardinals vs Reds moneyline: Cardinals -118, Reds +110
- Cardinals vs Reds over/under: 9 (-115o / -105u)
- Cardinals vs Reds spread: Cardinals -1.5 (+130), Reds +1.5 (-156)
Cardinals vs Reds Probable Pitchers
| Andre Pallante | Stat | Rhett Lowder |
|---|---|---|
| 12-6 | W-L | 4-8 |
| 2.2 | fWAR (FanGraphs) | 1.2 |
| 3.46 / 3.83 | ERA / xERA | 5.15 / 5.20 |
| 3.73 / 3.99 | FIP / xFIP | 4.50 / 4.68 |
| 9.6 | K-BB% | 8.7 |
| 55.6 | GB% | 42.1 |
| .276 | BABIP | .303 |
| 97 | Stuff+ | 86 |
| 104 | Location+ | 104 |
Cardinals vs Reds MLB Betting Preview
Action PRO projects Reds starter Rhett Lowder for 3.73 strikeouts in Game 2 against the Cardinals, giving us a solid 7.2% edge against the market when compared to his current prop line of over/under 4.5 strikeouts.
Cardinals vs Reds Pick, Betting Analysis
The biggest reason to trust this projection comes down to Lowder's style of pitching. Instead of overpowering hitters with high speed to get strikeouts, Lowder focuses on inducing weak ground balls and making batters beat themselves. He is a pitcher who relies on smart placement rather than big swing-and-miss stuff.
That approach makes it tough for him to rack up high strikeout numbers on any given night. Looking at his recent games, getting five strikeouts has been a tall order. He has stayed under 4.5 strikeouts in four of his last five starts.
To make matters harder for Lowder, the Cardinals are a tough opponent for this kind of setup. St. Louis has a patient, disciplined lineup that rarely chases bad pitches and excels at putting the ball in play, making quick outs rather than taking strike three.
Pick: Rhett Lowder Under 4.5 Strikeouts (-156, FanDuel)
