The Cleveland Guardians host the Toronto Blue Jays on September 1, 2026. First pitch from Progressive Field is scheduled for 6:40 p.m. EDT. The game will be broadcast on CLEG.
The Guardians are favored by -180 on the moneyline and by -1.5 on the run line. The Blue Jays are +150 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find our MLB picks and Blue Jays vs Guardians prediction below, as well as probable pitchers, weather report, and more.
Blue Jays vs Guardians Prediction
- Blue Jays vs Guardians Pick: Spencer Arrighetti Under 3.5 Strikeouts (+110)
Our Blue Jays vs Guardians best bet is on Spencer Arrighetti to record under 3.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Blue Jays vs Guardians Odds
| Blue Jays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -140 | 7.5 -120o / 100u | +150 |
| Guardians Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +120 | 7.5 -120o / 100u | -180 |
- Blue Jays vs Guardians moneyline: Blue Jays +150, Guardians -180
- Blue Jays vs Guardians over/under: 7.5 (-120o / +100u)
- Blue Jays vs Guardians spread: Guardians -1.5 (+120), Blue Jays +1.5 (-140)
Blue Jays vs Guardians Probable Pitchers
| Spencer Arrighetti (RHP, TPR) | Stat | Gavin Williams (RHP, CLE) |
|---|---|---|
| 7-7 | W-L | 12-7 |
| 0.2 | fWAR (FanGraphs) | 2.6 |
| 4.81/5.14 | ERA / xERA | 3.98/4.01 |
| 5.14/5.00 | FIP / xFIP | 3.72/2.86 |
| 9.7% | K-BB% | 24.5% |
| 35.2% | GB% | 43.5% |
| .254 | BABIP | .284 |
| 100 | Stuff+ | 105 |
| 90 | Location+ | 105 |
Blue Jays vs Guardians MLB Betting Preview
The Cleveland Guardians host the Toronto Blue Jays on Tuesday evening at Progressive Field, opening a fresh series after momentum-building performances over the weekend.
Cleveland comes off a dominant 11-1 victory against the Royals on Sunday, fueled by a breakout four-hit showing from Chase DeLauter.
Sitting at 69-68 overall and second in the AL Central, the Guardians look to refine their 32-36 home record, leaning heavily on a pitching staff that boasts a 3.73 team ERA, good for fourth in the American League.
Toronto enters Cleveland at 68-70 on the year, occupying fifth place in the competitive AL East while holding a 31-35 road mark.
The Blue Jays have shown clear explosive potential when power leads the way, sporting a sharp 24-12 record in games where they hit at least two home runs. Tuesday marks the fourth meeting between these two clubs this season.
On the mound, the Guardians send ace Gavin Williams to the rubber. Williams has enjoyed a stellar campaign, carrying a 12-7 record with a 3.98 ERA, a tiny 1.12 WHIP, and 204 strikeouts—making him one of only three pitchers in the American League to eclipse the 200-strikeout milestone this year.
Blue Jays vs Guardians Pick, Betting Analysis
Toronto hands the ball to right-hander Spencer Arrighetti, who carries a 7-7 record, a 4.81 ERA, and a 1.36 WHIP with 95 strikeouts across his combined body of work.
Arrighetti is still searching for his first victory in a Blue Jays uniform after being hit hard for a 7.36 ERA across his initial two starts with the club. Facing a disciplined Cleveland lineup that avoids high swing-and-miss rates, Arrighetti projects to struggle finding easy punchouts.
Action PRO projections target Arrighetti for just 3.12 strikeouts in this matchup against Cleveland. When weighed against his current prop line of Over/Under 3.5 Ks, this forecast creates a generous 14.4% value edge favoring the Under.
That model differential earns a top-tier A grade in our rating system.
Pick: Spencer Arrighetti Under 3.5 Strikeouts (+110)
