The NBA regular season is back in action with six matchups on the slate for this Wednesday. So, our staff of basketball betting experts dug into the latest odds and identified NBA best bets for all six of tonight's contests.
Continue below for our NBA best bets and predictions for Wednesday, February 25.
NBA Best Bets, Picks for Wednesday, February 25
| Game | Time (ET) | Pick |
|---|---|---|
  | 7:30 p.m. | |
  | 7:30 p.m. | |
  | 8 p.m. | |
  | 7:30 p.m. | |
  | 8 p.m. | |
  | 10 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NBA Odds page, which automatically surfaces the best lines for every game. | ||
Warriors vs. Grizzlies Spread Prediction
By Matt Moore
The Warriors may have lost to the Pelicans, but they showed what they are capable of in Sunday's game against Denver.
The Warriors still shoot a lot of threes, the most in the league — and Memphis gives up the seventh-most threes defensively.
The math game alone benefits the Warriors.
Memphis also is terrible at rim protection because, well, they aren’t playing any centers or really any bigs at all.
So, the Warriors’ back-cuts and lob attempts will be relatively unchallenged.
Memphis has some sneaky talented guys; I think Olivier-Maxence Prosper could have a big game and GG Jackson has the size to give an undersized Warriors team problems.
But ultimately, the Warriors have enough playoff-caliber rotation guys motivated to get this win after yesterday's loss.
Pick: Warriors -3.5 (-115)
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Thunder vs. Pistons Player Prop Pick
Action PRO is projecting 11.33 points for Jared McCain in the Thunder's matchup against the Pistons tonight, presenting a huge 24% egde against his current points prop line of over/under 8.5, which is strong enough to give the Over an A+ grade in our database.
After scoring totals of five and seven points in his first two games with the Thunder, McCain now enters tonight's matchup having scored 10+ points in four of his last five games, while eclipsing 12+ points in three of those contests and topping out at 21 points during that span.
The Thunder draw a tough matchup tonight against a Pistons squad that ranks 2nd in defensive rating and 4th in points allowed per game. However, McCain's prop line still appears to be too low in this spot.
You could also consider climbing the ladder with McCain to score 10+ points (+100) or 12+ points (+170) at DraftKings.
Pick: Jared McCain Over 8.5 Points (-125)
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Cavaliers vs. Bucks Prop Bet
By Joe Dellera
The Cavaliers play their second game in as many days tonight, as they face off against the Bucks in this spot.
One of the primary beneficiaries of the James Harden acquisition has been Jarrett Allen.
The duo developed incredible on-court chemistry almost immediately, as Allen is averaging 20.4 points per game with Harden vs. just 13.9 without him.
Allen is an excellent roll and lob threat for Harden, who continues to set him up perfectly.
Additionally, I would not be surprised if Evan Mobley sits here after being on a fairly strict minutes limit and this being a back-to-back set.
So, that could free up more usage for Jarrett Allen as well.
This is more of a bet on the Cavs' duo than a bet against the Bucks.
However, given that this is a clear let-down spot for Cleveland, that may also keep the game closer to help us avoid a blowout.
Pick: Jarrett Allen Over 15.5 Points (-114)
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Spurs vs. Raptors Total Prediction
By Bet Labs
This NBA totals betting system is built on the idea that strong traveling teams can drive pace and scoring in matchups where the market leans too heavily toward the under.
By focusing on regular season games outside of division play, the system avoids slower rivalry environments and taps into contests that tend to be more open and less physical.
It targets overs specifically when the betting public and money trends show a clear lean toward the under, creating a contrarian opportunity where expectations are suppressed but conditions for scoring remain strong.
The away team must be early enough in its season to still carry energy and identity, and it must also be coming off a decisive win, a signal that its offense and confidence are functioning at a high level.
When these elements align, strong road teams often set the tone, push pace, and elevate scoring beyond market expectations, making the over more attractive precisely when it is being overlooked.
Pick: Over 229.5 (-110)
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Kings vs. Rockets Spread Pick
By Matt Moore
The Rockets need a bounce-back win, and while they have been dreadful against the spread this season, this looks like a get-right spot against a Kings team playing a lot of its young guys heavy minutes.
It’s always possible Russell Westbrook just decides to play 36 minutes and go wild like he did vs. Memphis — but the more likely outcome here is a simple and easy Rockets win by double digits.
Sacramento got its win to break the losing streak, but the Kings are still a team coming off a massive losing streak.
Teams on the road against teams over .500 after breaking a 7-game losing streak or longer are slightly under .500 ATS and 6-8 since the Bubble.
With the Rockets so desperate to get back on track, and the Kings wanting to get back to tanking, this is directionally pretty opposite, even with how many points you have to lay with Houston in this spot.
Pick: Rockets -15 (-110)
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Celtics vs. Nuggets ATS Pick
By Bet Labs
This NBA spread betting system builds on the idea that Denver’s altitude creates a natural fatigue advantage when opponents arrive with limited rest and a recent stretch of road games.
In both the regular season and postseason, teams coming into Denver with only one day off and a multi-game road streak often struggle to maintain pace and efficiency in the second half, where the physical impact of playing in elevation becomes most visible.
By isolating situations where the Nuggets face opponents who are both travel-worn and unable to reset between games, the system targets a consistent performance edge rooted in fatigue, environment and the difficulty of adjusting quickly to Denver’s style and conditioning demands.
Pick: Nuggets -3.5 (-110)
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