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Bengals vs. Bills Odds & Betting Predictions - December 7, 2025

Bengals at Bills

9:25 pm • FOX

Cincinnati Bengals

3-7
@

Buffalo Bills

7-3

Bengals at Bills Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Bengals
3-7
N/A
N/A
N/A
Bills
7-3
N/A
N/A
N/A
location pinSunday 9:25 p.m.
December 07, 2025
Highmark StadiumOrchard Park

Bengals vs. Bills Props

Prop Projections

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Bengals vs. Bills Public Betting Percentages

Away Logo

Bengals

Public

Home Logo

Bills

50%

Bets%

50%

Money%

NFL Public Betting Right Arrow

Betting Trends

  • Bills are 4-1 in their last 5 games.
  • Bills are 2-3 in their last 5 games against the spread
  • Bills are 2-2 in their road games against the spread
  • The totals have gone OVER in 4 of Bills' last 5 games
  • The totals have gone OVER in 4 of Bills' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Bills		5-53-32-23-52-0
Bengals		3-72-31-41-22-5

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Bills		5-54-21-34-41-1
Bengals		7-35-02-32-15-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Bills		7-3N/AN/A5-32-0
Bengals		3-7N/AN/A2-11-6

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 16thTBW 44-32-6.5 WO 46.5BUF -305
Nov 9th@MIAL 13-30-8.5 LU 50MIA -445
Nov 2ndKCW 28-21+2.5 WU 53BUF +114
Oct 26th@CARW 40-9-7 WO 47.5BUF -395
Oct 13th@ATLL 14-24-3.5 LU 49.5ATL -202

Bengals vs. Bills Injury Updates

Bengals Injuries

  • Samaje Perine
    RB

    Perine is out with ankle

    Out

  • Mike Gesicki
    TE

    Gesicki is out with pectoral

    Out

  • Tanner Hudson
    TE

    Hudson is out with concussion

    Out

  • Joe Burrow
    QB

    Burrow is out with toe

    Out

Bills Injuries

  • Mitch Wishnowsky
    P

    Wishnowsky is out with back

    Out

  • Tyler Bass
    K

    Bass is out with hip

    Out

  • Dalton Kincaid
    TE

    Kincaid is out with hamstring

    Out

See more NFL Injuries Right Arrow
Player Stats
  • passing yards
    Josh Allen logo
    Josh Allen
    2456
    pyds
  • passing touchdowns
    Josh Allen logo
    Josh Allen
    18
    ptd
  • rushing yards
    James Cook logo
    James Cook
    968
    ryds
  • rushing touchdowns
    Josh Allen logo
    Josh Allen
    10
    rtd
Depth Charts
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Starter2ND3RD4TH
QBJosh AllenMitchell TrubiskyShane Buechele
RBJames CookRay DavisTy JohnsonFrank Gore
WRKhalil ShakirElijah MooreStephen Gosnell
TEDalton KincaidDawson KnoxJackson HawesKeleki Latu
LTDion DawkinsTylan GrableChase LundtTravis Clayton
LGDavid EdwardsKendrick Green
CConnor McGovernSedrick Van Pran-Granger
RGO'Cyrus TorrenceAlec Anderson
RTSpencer BrownRyan Van Demark
LDEGreg RousseauLandon JacksonJavon Solomon
WLBMatt MilanoDorian WilliamsKeonta Jenkins
MLBTerrel BernardJoe AndreessenShaq Thompson
LCBChristian BenfordMaxwell HairstonDorian Strong
SSCole BishopCam LewisWande Owens
FSTaylor RappDamar HamlinJordan Hancock
RCBTre'Davious WhiteDane JacksonJa'Marcus Ingram
PRBrandon Codrington
KRBrandon CodringtonElijah Moore
LSReid Ferguson
RWRKeon ColemanCurtis Samuel
FBReggie Gilliam
NTDaQuan JonesDeone WalkerZion Logue
LWRJoshua PalmerTyrell Shavers
NBTaron JohnsonBrandon Codrington
KTyler Bass
DTEd OliverT.J. SandersDeWayne Carter
Team Stats

Passing

2257
YDS
2398
236/373
Comps/Atts
207/299
6.432
YPA
8.395
20/11
TDs/INTs
18/7
23/142
Sacks/Yards
20/112

Rushing

814
Rush Yards
1476
191
Attempts
301
4.262
YPC
4.904
5
TDs
19

Turnovers

Fumbles Lost
11
Interceptions
7

Efficiency

17/28 60.71%
Redzone
24/36 66.67%
51/124 0%
3rd Down
53/118 0%
5/7 0%
4th Down
5/10 0%

First Downs

191
Total
224
115
Pass
121
52
Rush
79
24
Penalty
24

Misc

/
Penalties/Yards
/
Possession

Bengals vs. Bills Odds Comparison

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Bengals at Bills Team Totals

MatchupOverUnder
Bengals
3-7
N/A
N/A
Bills
7-3
N/A
N/A