The Los Angeles Rams (5-4) and Arizona Cardinals (3-6) will face off today in NFL Week 10. Kickoff is set for 4:05 p.m. ET from State Farm Stadium in Glendale, Ariz. The game will broadcast live on CBS.
The Rams are 9.5-point favorites over the Cardinals on the spread, with the over/under set at 39.5. Los Angeles is a -500 moneyline favorite to win outright, while Arizona is a +385 underdog to pull off the upset.
Let's get into my Rams vs Cardinals predictions and NFL picks for Sunday, November 15.
Rams vs Cardinals Prediction
- Rams vs Cardinals pick: Under 39.5 (-110)
My Rams vs. Cardinals best bet is the total to stay under 39.5 points, with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NFL odds page.
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Rams vs Cardinals Odds
| Rams Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-9.5 -110 | 39.5 -110o / -110u | -500 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+9.5 -110 | 39.5 -110o / -110u | +385 |
- Rams vs Cardinals Spread: Rams -9.5, Cardinals +9.5
- Rams vs Cardinals Total: 39.5
- Rams vs Cardinals Moneyline: Rams -500, Cardinals +385
Rams vs Cardinals NFL Week 10 Preview
Los Angeles Rams Betting Preview
The Rams are massive 9.5-point road favorites entering this game, but their offense is completely devoid of its usual explosiveness.
Matthew Stafford simply doesn't look right, and the wide receiver room has been completely decimated by injuries. With Puka Nacua and Davante Adams out, and Jordan Whittington landing on IR, the Rams are rolling out Konata Mumpfield and Tutu Atwell on the perimeter.
Rams head coach Sean McVay will be forced to play a ton of heavy tight-end sets just to piece together a functional passing game.
Arizona Cardinals Betting Preview
The Cardinals are in an equally dire situation offensively. Carson Beck is being thrown to the wolves to make his first career NFL start behind a patchwork offensive line.
The Cardinals are also down to their third-string left tackle and a backup center. During his college career, Beck's metrics plummeted when he was forced to throw under pressure, and he rarely had to face it behind elite offensive lines at Miami and Georgia.
Now, he has to face a fierce Rams defensive front featuring Aaron Donald and Myles Garrett with hardly any reliable receiving options beyond Trey McBride at tight end.
The Cardinals' receiver room currently consists of Reggie Virgil, Devin Duvernay, Harrison Wallace III, and Simi Fehoko. They quite literally have no downfield threats to keep the defense honest.
Rams vs Cardinals Prediction, Betting Analysis
This game is going to be very ugly. The market has already smashed this total down from 46.5 to 39, and I still lean heavily toward the under.
Neither team has the perimeter weapons to stretch the field, and Carson Beck is going to be under constant duress.
I expect a 19-6 type of game where the only touchdown might come from a defensive turnover.
Pick: Under 39.5 (-110)
