We have a shortened, 13-game slate on Monday, starting with Yankees vs. Tigers at Comerica Park (6:10 PM ET) on YES, and closing with Braves vs. Padres at Petco Park (10:10 PM ET) on ESPN.
Our experts have analyzed the matchups and found great options for Monday, June 22.
Below are 5 expert MLB best bets today.
MLB Best Bets Today
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 6:10 PM | |
  | 7:10 PM | |
  | 7:40 PM | |
  | 7:45 PM | |
  | 9:38 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Jon Anderson's Yankees vs Tigers Best Bet
By Jon Anderson
Does Gerrit Cole have an average fastball? That's what the numbers suggest. Some numbers on Cole's heater through 172 offerings:
- 100.2 Stuff+ (league average = 100)
- 8.1% Swinging Strike Rate (league average = 10.5%)
- 52% Strike Rate (Whiffs + Called + Fouls) (league average = 49%)
- 31% Ball% (league average = 34%)
- 96.6 mph (league average = 94.7)
The Tigers seem to have a big advantage when it comes to hitting the long ball tonight, which would sound crazy given that the Yankees have hit 28 more home runs this season. But Detroit sends Framber Valdez and his 52% ground-ball rate to the mound, and the lefty should neutralize plenty of the Yankees' biggest threats from the left side of the plate.
Framber vs. lefties this year: 28% K%, 7% BB%, .261 xwOBA
We have mid-70s temperatures with decently high humidity for this game, so I expect Cole's fastball to get hit into the stands once or twice. The most likely players to do that would be:
- Riley Greene +415 on DraftKings
- Kerry Carpenter +482 on DraftKings
- Dillon Dingler +563 on DraftKings
I like those home run bets, but most of all, I'm backing Carpenter to go yard.
Pick: Kerry Carpenter Home Run
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Sean Paul's Cubs vs Mets ML Prediction
By Sean Paul
Shota Imanaga is having a season that perfectly details what makes him both good and bad. He has a 4.26 ERA with a 3.64 xERA and 4.58 FIP. That's not bad, but he’ll never be a top-two pitcher for a winning team’s rotation due to his terrible 1.77 HR/9.
In June, the Cubs offense has gotten on track, posting a 123 wRC+ with a 10.7% walk rate (third best), a 20.7% strikeout rate (ninth), and 23 home runs (12th). After a nightmare month of May, things are back where they should be for the Cubs.
Starting pitching remains the biggest issue for New York — and one of the biggest problems is Kodai Senga. Although it’s just a five-start sample, Senga owns a 9.00 ERA with a 5.11 xERA and 6.81 FIP.
Senga walked at least two hitters in each of his five outings and has a 6.39 BB/9. Senga has always dealt with walk issues, which is fine if he keeps his HR/9 below 1.00 like he did last year. This year, his HR/9 is up to 2.63 — an unsustainable number, but he's an extreme fly-ball pitcher getting barreled 11.8% of the time. In 2023, his barrel rate was 6.5%; last year, it was 8%.
In all, I just can't back Senga in his current form. The stuff is strong, but this Cubs lineup is happy to take pitches and make the opposition work. If Senga can't find the zone, Chicago will make him pay and put up a crooked number.
Pick: Cubs Moneyline (-130 or Better)
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PRO's Dodgers vs Twins Top Prop Edge
By Action PRO
PRO projects Dodgers SP Eric Lauer for 3.16 strikeouts in tonight's matchup against the Twins, giving us a solid 15.9% edge against the market when compared to his current prop line of over/under 3.5, which is good enough to mark the under with an A- grade in our system.
He has fanned just 14 batters in 22 and 1/3 innings this season, with a strikeouts percentage of 16.0%, a noticeable drop from 24.7% and 23.9% in 2024 and 2025, respectively.
Lauer has gone under this line in six of his 12 games this year.
At plus money, let's fade him on his K line against San Diego.
Pick: Eric Lauer Under 3.5 Strikeouts (+121)
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Erik Beimfohr's Diamondbacks vs Cardinals Pick
Merrill Kelly is completely cooked, with a strikeout rate down to 13.6% this season and an absurd 15.2% barrel rate allowed.
He's been particularly dreadful against lefties, allowing a .438 xwOBA and tons of power.
The Diamondbacks' bullpen also has just two lefties, and one of them may be unavailable tonight, while nearly all of the Cards' best hitters are left-handed.
Pick: Cardinals Over 4.5 Team Total (-105)
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Jon Anderson's Orioles vs Angels Prop
By Jon Anderson
It's a Kyle Bradish night for the O's. This one comes five days after he racked up 18 whiffs and 12 strikeouts against the Mariners. That was his first start with more than seven strikeouts since May 8. So what happened last time? Was there any change we can rely on to stick in this juicy matchup with the Halos? It looks like the answer is yes, as his Stuff+ jumped to a season-high 107 in that outing.
Now he gets this Angels lineup, which doesn't have Mike Trout and still carries plenty of swing-and-miss. Check out some of the strikeout rates for the projected lineup:
- Christian Moore 35%
- Logan O'Hoppe 31%
- Denzer Guzman 29%
- Zach Neto 28%
- Jo Adell 26%
- Jose Siri 24%
He's the No. 1 scoring pitcher in the sim model today. He edges out Gerrit Cole, Gavin Williams, Drew Rasmussen and Hunter Brown for the top spot.
Pick: Kyle Bradish Over 6.5 Strikeouts (-104)
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