The Detroit Pistons (22-6) and Portland Trail Blazers (12-16) will face off in the NBA tonight. Tipoff is set for 10:00 p.m. ET from the Moda Center in Portland, Oregon. The game will broadcast live on KUNP.
The Pistons are 6-point favorites over the Blazers on the spread (Pistons -6), with the over/under set at 234.5 total points. Detroit is a -240 favorite to win outright on the moneyline, while Portland is +200 to pull off the upset.
Let's get into my Pistons vs. Trail Blazers predictions and NBA picks for Monday, December 22.
My Pistons vs Trail Blazers Prediction
- Pistons vs Trail Blazers pick: Over 234.5 (-110)
My Pistons vs Trail Blazers best bet is on the over, with the best price currently available at bet365. However, make sure to find the best odds by checking our live NBA odds page.
Pistons vs Trail Blazers Odds
| Pistons Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-6 -110 | 234.5 -110o / -110u | -240 |
| Trail Blazers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+6 -110 | 234.5 -110o / -110u | +200 |
Pistons vs Trail Blazers NBA Preview
This NBA totals system is built on the idea that strong traveling teams can drive pace and scoring in matchups where the market leans too heavily toward the under, which appears to be the situation entering tonight't matchup between the Pistons and Trail Blazers.
By focusing on regular season games outside of division play, the system avoids slower rivalry environments and taps into contests that tend to be more open and less physical.
It targets overs specifically when the betting public and money trends show a clear lean toward the under, creating a contrarian opportunity where expectations are suppressed but conditions for scoring remain strong.
The away team must be early enough in its season to still carry energy and identity, and it must also be coming off a decisive win, a signal that its offense and confidence are functioning at a high level — and the Pistons perfectly fit that mold.
When these elements align, strong road teams often set the tone, push pace, and elevate scoring beyond market expectations, making the over more attractive precisely when it is being overlooked.
So, let's take the over at 234.5 in Pistons-Blazers on Monday night.
Pistons vs Trail Blazers Betting Prediction
- Over 234.5 (-110)
Spread
I'm not betting either side of the spread in this game.
Moneyline
No play on the moneyline.
Over/Under
My Trail Blazers vs Pistons betting prediction is on the over at 234.5 total points.
