Colts vs. Chiefs Odds, Picks & Betting Predictions for Sunday Night Football

Colts vs. Chiefs Odds, Picks & Betting Predictions for Sunday Night Football article feature image
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Jay Biggerstaff-USA TODAY Sports. Pictured: Patrick Mahomes

  • The Kansas City Chiefs host the Indianapolis Colts in a Sunday Night Football showdown featuring the highest over/under of Week 5.
  • You'll find our staff's full coverage of the most important betting angles below, featuring an analysis of the odds and expert picks.

Colts at Chiefs Odds, Picks & Betting Predictions

  • Spread: Chiefs -10.5
  • Over/Under: 56
  • Time: 8:20 p.m. ET
  • TV Channel: NBC

Odds as of Sunday afternoon and via PointsBet, where Action Network users get an exclusive 200% deposit match (deposit $50, bet with $150).


Sunday Night Football Betting Guide

Our analysts and experts break down the most important angles of this game.

Here’s an excerpt, but you can read the full thing here.

You might point to the Colts’ powerful rushing attack as the biggest advantage — they are playing an abysmal Chiefs run defense that’s allowing a league-worst 5.9 yards per carry. And while Indy should have some success on the ground, Marlon Mack isn’t fully healthy, and the Chiefs should be able to load the box against a one-dimensional Colts offense that’s dealing with injuries at receiver.

Even with a healthy T.Y. Hilton, the Colts just don’t have much of a downfield passing attack with Jacoby Brissett under center. The Colts are averaging only 6.2 yards per attempt (27th in the NFL).

Even though the Colts’ dominant run-blocking offensive line should get push up front, this has blowout written all over it. In a matchup of two poor run defenses, the huge discrepancy in talent and ability of the Chiefs’ offense should reign supreme.

Here’s our full betting breakdown for Colts-Chiefs here.

Our Experts’ Colts vs. Chiefs Picks

Our staff breaks down how they’re betting the highest total of Week 5. There’s even a live bet and first-half spread in the mix. See their three picks.

Live Betting Colts-Chiefs

There’s one bet Sean Koerner is looking to make in-game. See which line he’s looking for.

Best SNF Prop Bets

  • Jacoby Brissett’s Rushing Yards
  • Damien Williams’ Receiving Yards
  • Jack Doyle’s Receiving Yards

These are the best player prop bets for Sunday night according to our tools. Here’s how to bet all three.

DFS Showdown Slate

Cash game strategy. Core GPP plays. Stacks. Chris Raybon breaks down how to play the single-game slate.

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