Padres vs. Cubs Odds & Betting Predictions - October 1, 2025

Padres at Cubs

7:08 pm • ABC
@
Starting Pitchers
pitcherteameraw-l
Andrew Kittredge logoA.KittredgeChicago Cubs logo0.000-0
Dylan Cease logoD.CeaseSan Diego Padres logo0.000-0

Padres at Cubs Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Padres
90-72
-1.5
-1.5+171
o6.5-108
-102
Cubs
92-70
u7
+1.5-207
u6.5-112
-118
location pinWednesday 7:08 p.m.
October 01, 2025
Wrigley FieldChicago
thermometer image74°Fahrenheit
rain image0%Rain
wind image8Wind
Padres vs. Cubs Expert Picks
💰🦡 Jake
💰🦡 Jake
Last 30d: 99-120-6 (+30.8u)
SD o3.5+124
1u
Lines at Lunch
Lines at Lunch
Last 30d: 89-88-3 (-5.2u)
Over 3.5 (F5)+105
0.95u
Ryan Sura
Ryan Sura
Last 30d: 99-93-2 (+7.4u)
Over 3.5 (F5)+105
1u
Lines at Lunch
Lines at Lunch
Last 30d: 89-88-3 (-5.2u)
SD -102
1.02u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 56-67-5 (+4.5u)
CHC -110
1u
@Zerillo
D.Cease u14.5 Outs-115
1u
@Zerillo @cowhitchurch https://myaction.app/irmZJtM46Wb
Cam Is Money
Cam Is Money
Last 30d: 55-70-3 (-14.1u)
CHC -113
1u
Sean Zerillo
Sean Zerillo
Last 30d: 146-180-4 (-14.8u)
D.Cease u14.5 Outs-141
0.14u
Bet to -155
Lines at Lunch
Lines at Lunch
Last 30d: 89-88-3 (-5.2u)
SD +102
0.98u
Brian Bitler
Brian Bitler
Last 30d: 73-72-1 (-4.6u)
CHC -112
3u
Anders
Anders
Last 30d: 11-13-0 (-1.6u)
CHC -106
1.06u
Analysis on Tiktok… I’d play to -120
Brandon Kravitz
Brandon Kravitz
Last 30d: 44-51-0 (-4.4u)
Under 6.5+100
1u
Sandy Plashkes
Sandy Plashkes
Last 30d: 70-106-3 (-18.5u)
SD +102
1u
Sean Zerillo
Sean Zerillo
Last 30d: 146-180-4 (-14.8u)
CHC -104
1.04u
Bet to -115

Padres vs. Cubs Previews & Analysis

  • 2 Data-Driven HR Picks (51-1 Parlay) article feature image

    2 Data-Driven HR Picks (51-1 Parlay)

    Leo Tesler
    Oct 1, 2025 UTC
  • BET the Cubs ML in Game 2 vs Padres! | MLB Playoff Best Bets | Payoff Pitch article feature image

    BET the Cubs ML in Game 2 vs Padres! | MLB Playoff Best Bets | Payoff Pitch

    Collin Whitchurch
    Oct 1, 2025 UTC
  • Today's MLB Best Bets article feature image

    Today's MLB Best Bets

    Action Network Staff
    Oct 1, 2025 UTC
  • Zerillo's Opening Pitch for Game 2 of the AL WC Round article feature image

    Zerillo's Opening Pitch for Game 2 of the AL WC Round

    Sean Zerillo
    Oct 1, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

Right Arrow
Right Arrow

No props found

Line Movement Tracker

Right Arrow
Right Arrow

Padres vs. Cubs Public Betting Percentages

Away Logo

Padres

Public

46%

Bets%

54%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cubs
79-8336-4543-3833-5045-32
Padres
82-7835-4547-3343-5737-19

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cubs
75-81-634-46-141-35-540-39-434-41-2
Padres
81-74-544-34-237-40-351-44-528-28

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cubs
92-7044-3739-4245-3837-40
Padres
4-345-3547-3358-4231-25

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 30thSDW 3-1-1.5 WU 6.5CHC -133
Sep 28thSTLW 2-0-1.5 WU 7CHC -155
Sep 27thSTLW 7-3-1.5 WO 9.5CHC -178
Sep 26thSTLW 12-1-1.5 WO 9CHC -184
Sep 25thNYML 5-8+1.5 LO 7.5NYM -103

Cubs vs. Padres Injury Updates

Cubs Injuries

  • Michael Soroka
    P

    Soroka is out with shoulder

    Out

  • Justin Steele
    P

    Steele is out for season with elbow

    Out for Season

Padres Injuries

  • Joe Musgrove
    P

    Musgrove is out for season with elbow

    Out for Season

Padres vs. Cubs Starting Lineups
Padres Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Dylan Cease logoRD.Cease, P8-124.551.32711.52
HITTERSAVGOBPSLGHR
Fernando Tatis logo1F.Tatis, RF.268.368.44625
Luis Arraez logo2L.Arraez, 1B.292.327.3928
Manny Machado logo3M.Machado, 3B.275.335.46027
Jackson Merrill logo4J.Merrill, CF.264.317.45716
Xander Bogaerts logo5X.Bogaerts, SS.263.328.39111
Ryan O'Hearn logo6R.O'Hearn, DH.283.374.46313
Gavin Sheets logo7G.Sheets, LF.252.317.42919
Jake Cronenworth logo8J.Cronenworth, 2B.246.367.37711
Freddy Fermin logo9F.Fermin, C.255.309.3393
Cubs Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Andrew Kittredge logoRA.Kittredge, P2-23.451.0859.19
HITTERSAVGOBPSLGHR
Michael Busch logo1M.Busch, 1B.261.343.52334
Nico Hoerner logo2N.Hoerner, 2B.297.345.3947
Ian Happ logo3I.Happ, LF.243.342.42023
Kyle Tucker logo4K.Tucker, DH.266.377.46422
Seiya Suzuki logo5S.Suzuki, RF.245.326.47832
Carson Kelly logo6C.Kelly, C.249.333.42817
Pete Crow-Armstrong logo7P.Crow-Armstrong, CF.247.287.48131
Dansby Swanson logo8D.Swanson, SS.244.300.41724
Matt Shaw logo9M.Shaw, 3B.226.295.39413

Padres vs. Cubs Odds Comparison

Right Arrow

Could not load odds

Padres at Cubs Team Totals

MatchupOverUnder
Padres
90-72
N/A
N/A
Cubs
92-70
N/A
N/A