The Chicago White Sox host the Cincinnati Reds on August 12, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. ET. The game will be broadcast on CINR.
The White Sox are favored by -138 on the moneyline and by -1.5 on the run line. The Reds are +128 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.
Find our MLB picks and Reds vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Reds vs White Sox Prediction
- Reds vs White Sox Pick: Reds Moneyline (+128)
Our Reds vs White Sox best bet is on Cincinnati to win outright. Make sure to find the best odds by checking our live MLB odds page.
Reds vs White Sox Odds
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -170 | 8.5 -115o / -105u | +128 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +140 | 8.5 -115o / -105u | -138 |
- Reds vs White Sox moneyline: Reds +128, White Sox -138
- Reds vs White Sox over/under: 8.5 (-115o / -105u)
- Reds vs White Sox spread: Reds +1.5 (-170), White Sox -1.5 (+140)
Reds vs White Sox Probable Pitchers
| Rhett Lowder (RHP, CIN) | Stat | Luis Castillo (RHP, CHW) |
|---|---|---|
| 4-7 | W-L | 3-9 |
| 1.1 | fWAR (FanGraphs) | 0.6 |
| 5.26 / 5.27 | ERA / xERA | 5.30 / 4.84 |
| 4.50 / 4.73 | FIP / xFIP | 4.56 / 4.43 |
| 8.5 | K-BB% | 12.6 |
| 42.0 | GB% | 36.5 |
| .300 | BABIP | .305 |
| 86 | Stuff+ | 97 |
| 104 | Location+ | 109 |
Reds vs White Sox MLB Betting Preview
Sean Zerillo's projections show solid value on the Reds moneyline tonight against the White Sox.
If you want to dive deeper into this matchup, it'd be wise to check out BARTOLO, Zerillo's new PRO baseball tool that gives you access to all the input data he uses to project games every day.
Reds vs White Sox Pick, Betting Analysis
BARTOLO projects a 3.7% edge on the Reds moneyline for this matchup, grading their lineup with an A+ for power and eye.
Cincinnati will send Rhett Lowder to the mound, and he's coming off three very solid outings in a row, giving up only two earned runs in each of them against strong the Cardinals, Pirates, and Athletics.
Meanwhile, White Sox SP Luis Castillo had it tougher against the Dodgers and Red Sox, allowing 10 runs and 10 hits in nine innings combined in his past two starts.
Over the past two weeks, the Reds lineup has performed better than its counterpart, with Cincinnati ranking 20th in wRC+ while Chicago sits 22nd.
Pick: Reds ML (+128, FanDuel)
