The Cincinnati Reds host the San Diego Padres on September 1, 2026. First pitch from Great American Ball Park is scheduled for 6:40 p.m. EDT. The game will be broadcast on SDPA.
The Padres are favored by -140 on the moneyline and by -1.5 on the run line. The Reds are +115 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.
Find our MLB picks and Padres vs Reds prediction below, as well as probable pitchers, weather report, and more.
Padres vs Reds Prediction
- Padres vs Reds Pick: Samad Taylor Over 0.5 Singles (+100)
Our Padres vs Reds best bet is on Samad Taylor to record 0.5 Singles. Make sure to find the best odds by checking our live MLB odds page.
Padres vs Reds Odds
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +115 | 9.5 -110o / -110u | -140 |
| Reds Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -140 | 9.5 -110o / -110u | +115 |
- Padres vs Reds moneyline: Padres -140, Reds +115
- Padres vs Reds over/under: 9.5 (-110o / -110u)
- Padres vs Reds spread: Padres -1.5 (+115), Reds +1.5 (-140)
Padres vs Reds Probable Pitchers
| Randy Vasquez (RHP, SDP) | Stat | Nick Lodolo (LHP, CIN) |
|---|---|---|
| 10-6 | W-L | 3-3 |
| 1.0 | fWAR (FanGraphs) | 0.0 |
| 4.02/5.69 | ERA / xERA | 5.24/6.60 |
| 4.39/4.87 | FIP / xFIP | 5.60/4.79 |
| 8.1% | K-BB% | 8.6% |
| 40.7% | GB% | 41.5% |
| .282 | BABIP | .314 |
| 97 | Stuff+ | 106 |
| 103 | Location+ | 90 |
Padres vs Reds MLB Betting Preview
Manny Machado is riding high after a spectacular four-hit outing on Monday, leading the San Diego Padres (73-65, second in the NL West) into Tuesday's matchup against the Cincinnati Reds (65-73, fifth in the NL Central) at Great American Ball Park.
The first pitch is scheduled for 6:40 p.m. EDT in Cincinnati, marking the fifth meeting between the two clubs this year, with San Diego holding a 3-1 edge in the season series.
Both clubs come into this game with matching 32-37 records away from their home comforts, but the Padres have proven exceptionally tough to beat when their offense clicks, boasting a 51-8 mark when scoring at least five runs.
Right-hander Randy Vasquez (10-6, 4.02 ERA, 1.28 WHIP, 76 strikeouts) takes the mound for San Diego.
Vasquez has been in sublime form lately, posting a 4-0 record with a stingy 2.20 ERA over 32 2/3 innings across his last six appearances (four starts).
Cincinnati counters with southpaw Nick Lodolo (3-3, 5.24 ERA, 1.54 WHIP, 64 strikeouts), who looks to bounce back after giving up four earned runs in four frames against the Giants in his previous outing.
Padres vs Reds Pick, Betting Analysis
Action PRO projects utility man Samad Taylor to collect 0.98 singles in Tuesday's matchup against the Reds' pitching staff.
Comparing this projection of nearly one full single to his current prop line set at over/under 0.5 singles reveals a solid 12.5% edge against the market.
The Padres recently activated the 28-year-old infielder/outfielder from the 10-day injured list after he missed time since early July with a right oblique strain.
Taylor's return provides depth while Gavin Sheets heads to the IL with a foot issue.
When healthy this season, Taylor has produced efficiently, slashing .330/.410/.398 with a homer, 11 RBI, and six stolen bases over 102 plate appearances across 26 games.
Prior to his injury, he recorded a single in three consecutive games and four of his last five overall, making Over 0.5 Singles a high-value play as he returns to the lineup.
Pick: Samad Taylor Over 0.5 Singles (+100)
