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Clippers vs Hornets Prediction, Pick, Odds for Saturday, November 22

Clippers vs Hornets Prediction, Pick, Odds for Saturday, November 22 article feature image
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Bill Streicher and Jim Dedmon-Imagn Images. Pictured: James Harden and LaMelo Ball

The Los Angeles Clippers (4-11) and Charlotte Hornets (4-11) will face off in the NBA tonight. Tipoff is set for 1:00 p.m. EST from Spectrum Center in Charlotte, N.C. The game will broadcast live on FDSSE.

The Clippers are -1.5 favorites over the Hornets on the spread (Clippers -1.5), with the over/under set at 227.5 total points. Los Angeles is a -120 favorite to win outright on the moneyline, while Charlotte is +105 to pull off the upset.

Let's get into my Clippers vs. Hornets predictions and NBA picks for Saturday, November 22.


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My Clippers vs Hornets Prediction

  • Clippers vs Hornets pick: Hornets ML +105

My Hornets vs Clippers best bet is on the Hornets moneyline, with the best price currently available at bet365. But as always, make sure to find the best odds by checking our live NBA odds page.


Clippers vs Hornets Odds

Clippers Logo
Saturday, Nov 22
1 p.m. ET
FDSSE
Hornets Logo
Clippers Odds
SpreadTotalMoneyline
-1.5
-110
227.5
-110o / -110u
-120
Hornets Odds
SpreadTotalMoneyline
+1.5
-110
227.5
-110o / -110u
+105
Odds via bet365. Get up-to-the-minute NBA odds here.
bet365 Logo

Clippers vs Hornets NBA Preview

Two teams, seemingly on a freefall, faced off against each other.

The Clippers, obviously, are the most concerned. Injuries have hit them hard, and the loss of Bradley Beal due to a season-ending hip surgery leaves the team leaning too heavily on James Harden to carry their offense.

That's because Kawhi Leonard will miss his 10th game while dealing with ankle issues, a frustrating constant by now, and Jordan Miller and Derrick Jones Jr. are also out.

Los Angeles has lost three in a row and is 1-9 in the last 10 games, so if Charlotte wants to break its own four-game losing streak, this is their chance.

The Hornets have performed much better at home (3-4) than on the road (1-7), and it's not like their losses at Spectrum Center were against nobodies.

The Thunder, Lakers, Timberwolves and Magic were the teams that came out on top there, while the Hornets have beaten the Nets, Jazz and Bucks at home.

Charlotte has also dealt with fitness issues early this season, but today the team will welcome Brandon Miller back to the lineup after missing 13 games with a shoulder injury.

This aligns with our Bet Labs system recommendation to back the home 'dog on Saturday.


Clippers vs Hornets Prediction, Betting Analysis

The "Undervalued vs. Bad Defense" system identifies NBA regular-season matchups where efficient but undervalued teams face opponents with poor defensive metrics.

When a team’s underlying performance indicators, such as Pythagorean strength, exceed public perception, the betting market often undervalues them against weak defensive opponents who allow high scoring efficiency.

These games typically feature modest moneylines that signal balance but overlook the defensive mismatch.

Slight movement toward the undervalued side reinforces that bettors are slowly recognizing the edge, yet the market remains mispriced.

Over recent seasons, this pattern has rewarded teams whose true performance levels are masked by variance while exploiting opponents that consistently fail to contain efficient offenses, creating a steady opportunity on the moneyline.

NBA Icon
Evan Abrams – Undervalued vs. Bad Defense (SEASON)
the game is played during the Regular season
the opposing team's average points allowed is between 110 and 1000
the opposing team's defensive efficiency is between 110 and 1000
the team's Pythagorean +/- is between 2% and 100%
the closing moneyline is between -205 and 131
the spread change from open to close is between -100 and -0.5
the game was played during the 2025-26 or 2024-25 or 2023-24 or 2022-23 or 2021-22 or 2020-21 season
$1,447
WON
292-208-0
RECORD
58%
WIN%

Pick: Hornets ML +105 (bet365)

Playbook

Hornets vs Clippers Betting Trends


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