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It has been a great day of college football action. Now, we're onto the final stretch.
Our college football staff came through with five best bets for Saturday night's slate, kicking off with three straight top-25 matchups and concluding with some late-night Mountain West action.
So, read below for four college football predictions and picks for the night games on Saturday, November 7.
Be sure to download the Action Network app for more expert picks and analysis!
College Football Predictions for Saturday Night
The team logos in the table below represent each of the matchups that our college football betting staff is targeting from Saturday night's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 6:15 p.m. | |
  | 7:30 p.m. | |
  | 7:30 p.m. | |
  | 7:45 p.m. | |
  | 10:30 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NCAAF Odds page, which automatically surfaces the best lines for every game. | ||
Kentucky vs. Tennessee Pick
Tennessee's defense is the unit to look out for here.
The Volunteers rank 10th in EPA/Pass allowed and ninth in late-down Success Rate allowed. It's going to be a tall task for Kentucky to move the ball down the field on this defense.
Tennessee has a strong rush offense, which is where Kentucky's biggest weakness is on defense. The Vols rank fifth in EPA/Rush, whereas Kentucky ranks 64th in EPA/Rush allowed.
Tennessee should get it done on the ground and open up the passing game, all while the defense shuts down the Kentucky offense.
Pick: Tennessee -6.5
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Georgia vs. Ole Miss Pick
There are a number of reasons to believe the Ole Miss defense won't have success in stopping Georgia. The Rebels sit outside the top 100 in penalties and third-down defense, a massive issue for a unit that's 119th in passing down explosives allowed.
The best attribute of the Ole Miss defense comes against the run, but the Rebels have yet to face an inside zone attack that uses 12 personnel like Georgia.
Man blocking assignments have been led by running back Nate Frazier, who's fully healed from a rib injury and averaged 5.6 yards per carry against Auburn. Ole Miss has been putrid against man blocking with a low 43% Success Rate.
Containing Trinidad Chambliss is priority No. 1 for Georgia.
Defensive coordinator Glenn Schumann called defense against Ole Miss twice last season, allowing 44 yards in scrambles. Georgia solved the Chambliss question in a playoff loss, keeping the Ole Miss quarterback from a single scramble. He totaled just 14 yards on designed run calls.
Chambliss was assisted by season highs in receiving from both Harrison Wallace III and De'Zhaun Stribling. Ellis Robinson IV has been a shutdown cornerback for the Bulldogs this season and is sure to draw the assignment against Deuce Alexander.
Keep tabs on Robinson after a knee injury against Florida, but Georgia head coach Kirby Smart indicated the news was positive for the corner this week.
Action Network's Betting Power Ratings call for Georgia to be a 7.5-point favorite, well ahead of a market favoring the Bulldogs by just 3.5.
The Ole Miss defense will be tasked with facing run concepts using a two-tight-end set while overproducing season-average numbers on third downs.
Georgia looked healthy in a demolition of Florida after the bye week, resolving any lingering injury issues with Frazier and quarterback Gunner Stockton.
The biggest question is whether or not Chambliss will be allowed to generate first downs on scrambles while connecting downfield.
Georgia contained the Chambliss scrambles in the SEC Championship but must show why it's 11th overall in coverage to beat Ole Miss.
Check out Wilson's full Week 10 betting card below:
Pick: Georgia -3.5
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Miami vs. Notre Dame Pick
By Stuckey
This is another spot I've had circled since last year's final College Football Playoff reveal show when the committee jumped Miami over Notre Dame.
I'm sure the Irish have also had this game marked since that day and will be hungry for revenge from last season's opening week loss at Miami in CJ Carr's first career start (in a game that could've gone either way).
This is essentially a playoff game for Notre Dame, which it has probably known for quite some time, so I'd expect the kitchen sink from the Irish (similar to what we saw from BYU against ND).
It wouldn't shock me if Notre Dame has been preparing for this game for months. A loss, and it's potentially out for a second straight season, which would be hard to imagine for a team I have power-rated in the top two in both years.
I originally projected this spread above a touchdown when accounting for the matchup and spot. And that was prior to star wide receiver Malachi Toney getting announced out with an ankle injury. Now, I'm closer to 10.
While it's difficult to nail down an exact number, I'd argue Toney is worth close to 2.5 points when you consider his production and the gravity he has on opposing defenses, which opens up everything else for the offense.
He's also a threat in the running game and puts the fear of God in opposing punters.
Toney averages 4.3 yards per route run, which leads the country. And he has absolutely shredded man coverage (which ND uses at a high clip) with an absurd 7.6 yards per route run. He has been targeted 83 times (50 more than everybody else on the team) and never drops anything.
To illustrate his impact another way, let's look at the on/off splits. It's not a huge sample size, but on drop backs with Mensah and Toney on the field together, Miami averages an asburd 10.2 yards per play. Conversely, on 34 drop backs with Mensah on the field without Toney, that number plummets to 5.6 (and Mensah's QBR falls from 95 to 42).
It would've been must-see TV to watch Toney battle star cornerback Leonard Moore, who I believe would've shadowed him, but now life becomes much easier for the star-studded Irish secondary.
Moore can now essentially erase Cooper Barkate, which will put added stress on others to step up. The trickle-down effect is significant.
It's worth noting that Notre Dame has a handful of key injuries on defense. I don't worry about any on the back end, but the defensive line could be compromised.
I'm sure that's what Mario Cristobal wants to test early and often, especially in a hostile environment without Toney.
However, it's not like Miami has had a completely dominant rushing attack so far in 2026. Don't get me wrong, the Hurricanes have been very good in that department, but I wouldn't put them in the elite category.
And it's not like this offensive line has faced a gauntlet of opposing defensive fronts. Can Miami sustain drives without Toney and finish them off with touchdowns? I have my doubts, and this ND defense is probably owed some positive regression in the red zone.
Now, the other side of the ball is where Notre Dame should really have an advantage against a Miami defense that has major issues in coverage (103rd in Passing Success Rate allowed).
The Hurricanes just made Billy Edwards Jr. (28-of-34, 344 yards, four TDs, 0 INTs) look like prime Tom Brady and even somehow allowed Tait Reynolds to throw for nearly 300 yards.
After that close loss to Miami, UNC head coach Bill Belichick noted that Miami ran the same thing it had been running all season with no adjustments.
Maybe that forces defensive coordinator Corey Hetherman's hand into making some alterations, but I doubt he can solve all of the coverage issues in just one week.
The Canes especially struggle to defend the middle of the field, which is not ideal against CJ Carr, who's one of the nation's most willing and efficient passers in that range.
Part of Miami's defensive woes have stemmed from injuries in the secondary, which may explain some of the lack of variation in looks Hetherman has offered on the back end.
The Canes also don't have the luxury of Rueben Bain Jr. and Akheem Mesidor wreaking havoc off the edge on every passing play, which made life easier for the entire secondary in 2025.
It's a similar story in Texas Tech following all of its own NFL departures up front. Miami also clearly misses Jakobe Thomas and Keionte Scott, who were Miami's best defensive backs last season.
It's just hard for me to envision Miami getting many stops after what I've seen UNC and Florida State do to this unit. And it's also worth mentioning that Miami has benefited from an 88% fumble recovery percentage (third-highest in the country) and a very biased ACC whistle in a number of games.
If a few bounces and calls actually go Notre Dame's way, the Irish should win this by double digits.
Over the past 10 seasons, including the postseason, Notre Dame has gone 27-8 ATS (77.1%) as a single-digit favorite, covering by an amazing nine points per game on average. The Irish are by far the most profitable team in that role over that period.
Check out all 13 of Stuckey's Week 10 situational spots below:
Pick: Notre Dame -7.5 or Better
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Oklahoma vs. Florida Pick
By Doug Ziefel
John Mateer’s passing floor has been steadier than his reputation, and bet365’s number is the lowest on the board.
He has cleared 190.5 in six of his eight games this season, with 225, 238, 231, 270, 283 and 244 yards. That’s an average of about 229 a game, and the two misses were 189 and 155.
Other books have this line between 199.5 and 203.5, so the 190.5 here gives you roughly 10 yards of cushion. Our PRO Projections have him closer to 242.
Oklahoma’s offense runs through his arm.
The Sooners’ ground game has been inefficient all season, and Mateer’s own rushing has been minimal, so Oklahoma has asked him to throw 40 or more times in two of its last three games, including 43 attempts against South Carolina last week.
Oklahoma is also a touchdown underdog, and trailing teams throw more.
Florida’s pass defense gives him room. The Gators allow about 236 passing yards a game at seven yards per attempt, and they have given up 271 to Auburn's Byrum Brown, 298 to Ole Miss' Trinidad Chambliss and 279 to South Carolina's LaNorris Sellers.
Florida’s strength is its pass rush and secondary, but Mateer also comes off a 283-yard, two-touchdown game at Mississippi State, which showed what he can do with clean pockets.
The change at offensive coordinator, with Jason Witten calling plays, is also a chance for new energy and a refreshed game plan.
Pick: John Mateer Over 190.5 Passing Yards (-115)
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Wyoming vs. UNLV Pick
By Kyle Hunter
Wyoming is 4-1 in the Mountain West. UNLV is 3-1 in the Mountain West. There's a lot on the line in this showdown in Las Vegas.
The Cowboys have looked like a completely different team in the last few weeks. The running game has really been working, as the Pokes are all the way up to fourth nationally in Offensive Line Yards and 22nd in Rushing Success Rate.
UNLV is weak against the run, sitting 138th in Defensive Line Yards, 129th in Rushing Success Rate allowed and 127th in rushing explosiveness allowed.
Opponents have racked up 15 carries of 20 yards or longer against this UNLV stop unit. That’s important since Wyoming has become much more explosive in the run game recently, ranking eighth nationally in rushing explosiveness.
Quarterback Tyler Hughes isn’t a star, but he has gotten a lot more comfortable in the Cowboys offense in recent weeks, so they can keep defenses honest.
UNLV gave up 430 rushing yards against Air Force. The Rebels allowed a very poor Northern Illinois team to put up 493 yards of total offense and 24 points last weekend.
The Rebels' defensive front is their weakness, and that plays to the strength of the Wyoming offense.
UNLV will run it well and hit some big plays in the rushing game as well, but I think Wyoming is being underrated, especially on offense.
Check out all of Hunter's Week 10 team total picks below:
Pick: Wyoming Team Total Over 19.5
