Chiefs vs. Chargers Odds & Betting Predictions - September 6, 2025
Chiefs at Chargers
12:00 am • YouTubeChiefs at Chargers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Chiefs 2-1 | -3 | -2.5-115 | o44.5-110 | -150 |
 Chargers 0-1 | u44.5 | +2.5-105 | u44.5-110 | +125 |
Chiefs vs. Chargers Previews & Analysis
Chiefs vs. Chargers Props
Prop Projections
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Prop Odds Comparison
Line Movement Tracker
Chiefs vs. Chargers Public Betting Percentages
Betting Trends
- Chargers are 5-0 in their last 5 games.
- Chargers are 5-0 in their last 5 games against the spread
- Chargers are 7-2 in their road games against the spread
- The totals have gone OVER in 3 of Chargers' last 5 games
- The totals have gone OVER in 5 of Chargers' 8 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Chiefs vs. Chargers Injury Updates
Chiefs Injuries
- Mike EdwardsS
Edwards is questionable with quad
Questionable
- Skyy MooreWR
Moore is doubtful with abdomen
Doubtful
- Rashee RiceWR
Rice is out with leg
Out
- Cam JonesLB
Jones is questionable with illness
Questionable
- Jared WileyTE
Wiley is out with knee
Out
Chargers Injuries
- Denzel PerrymanLB
Perryman is questionable with groin
Questionable
- Tyler ConklinTE
Conklin is questionable with calf
Questionable
- Trey PipkinsT
Pipkins is questionable with oblique
Questionable
- Jalen ReagorWR
Reagor is out with finger
Out
- Alohi GilmanS
Gilman is questionable with hamstring
Questionable
- Elijah MoldenCB
Molden is questionable with knee
Questionable
- Naquan JonesDT
Jones is questionable with elbow
Questionable
- Ja'Sir TaylorDB
Taylor is doubtful with oblique
Doubtful
- Deane LeonardDB
Leonard is questionable with hamstring
Questionable
- Quentin JohnstonWR
Johnston is questionable with thigh
Questionable
- Junior ColsonLB
Colson is questionable with ankle
Questionable
- Brenden RiceWR
Rice is out with shoulder
Out
- passing yards
Justin Herbert3870pyds - passing touchdownsJustin Herbert23ptd
- rushing yards
-905ryds - rushing touchdowns-9rtd
| Starter | 2ND | 3RD | 4TH | |
|---|---|---|---|---|
| QB | Justin Herbert | Easton Stick | ||
| RB | Gus Edwards | J.K. Dobbins | Jaret Patterson | Kimani Vidal |
| WR | Ladd McConkey | Derius Davis | ||
| TE | Will Dissly | Hayden Hurst | Stone Smartt | |
| LT | Rashawn Slater | Foster Sarell | Tyler McLellan | |
| LG | Zion Johnson | Karsen Barnhart | ||
| C | Bradley Bozeman | Brenden Jaimes | Bucky Williams | |
| RG | Trey Pipkins | Jamaree Salyer | ||
| RT | Joe Alt | |||
| LCB | Asante Samuel | Cam Hart | ||
| SS | Derwin James | Tony Jefferson | ||
| FS | Alohi Gilman | |||
| RCB | Kristian Fulton | Deane Leonard | ||
| P | JK Scott | |||
| H | JK Scott | |||
| PR | Derius Davis | Ladd McConkey | ||
| KR | Derius Davis | Ladd McConkey | ||
| LS | Josh Harris | |||
| DT | Otito Ogbonnia | Justin Eboigbe | ||
| LOLB | Joey Bosa | Tuli Tuipulotu | Tre'Mon Morris-Brash | Chris Collins |
| NT | Poona Ford | Christopher Hinton | Teair Tart | |
| RILB | Denzel Perryman | Nick Niemann | Shaq Quarterman | |
| LILB | Daiyan Henley | Junior Colson | Troy Dye | Jeremiah Jean-Baptiste |
| ROLB | Khalil Mack | Bud Dupree | Chris Rumph | |
| RWR | Joshua Palmer | Brenden Rice | Simi Fehoko | |
| NB | Ja'Sir Taylor | Tarheeb Still | ||
| DE | Morgan Fox | Scott Matlock | ||
| LWR | DJ Chark | Quentin Johnston | Jaylen Johnson | |
| K | Cameron Dicker |
Chiefs vs. Chargers Odds Comparison
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Chiefs at Chargers Team Totals
MatchupOverUnder | ||
|---|---|---|
Chiefs 2-1 | N/A | N/A |
Chargers 0-1 | N/A | N/A |