Broncos vs. 49ers Odds & Betting Predictions - October 4, 2026
Broncos at 49ers
8:25 pm • CBSBroncos at 49ers Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Broncos 4-2 | +2.5 | +3-110 | o48.5-105 | +140 |
49ers 6-0 | u46.5 | -3-109 | u48.5-112 | -166 |

Levi's StadiumSanta Clara
Broncos vs. 49ers Expert Picks
Matt Moore
Last 30d: 44-45-9 (+0.5u)
DEN +2.5+100
1.1u
Kody Malstrom
Last 30d: 66-55-1 (+2.2u)
SF -2.5-108
0.5u
Under 48.5-108
0.5u
Doug Ziefel
Last 30d: 393-392-9 (+31.9u)
K.Black u23.5 Rush Yds-114
0.5u
B.Nix u1.5 Pass TDs-122
0.5u
C.McCaffrey o39.5 Rec Yds-113
0.56u
Ryan Minion
Last 30d: 240-223-3 (+31.7u)
SF -2.5-114
$1.00
C.McCaffrey o39.5 Rec Yds-112
$1.12
OldSchool0909
Last 30d: 47-48-1 (+2.4u)
DEN +2.5-104
1u
DEN +2.5+100
1u
DEN +130
1u
Sandy Plashkes
Last 30d: 106-108-4 (+15.3u)
SF u24.5-105
1u
@Mjaybrxd
Brandon Anderson
Last 30d: 28-96-0 (-14.2u)
K.Black o22.5 Rush Yds-113
0.75u
Brandon’s playground pod Week 4
K.Black 40+ Rushing Yards Yes+306
0.15u
Brandon’s playground pod Week 4
K.Black 60+ Rushing Yards Yes+960
0.1u
Brandon’s playground pod Week 4
K.Black 50+ Rushing Yards Yes+560
0.15u
Brandon’s playground pod Week 4
Kyle Murray
Last 30d: 152-135-9 (+21.4u)
R.Harvey o3.5 Recs+102
1.02u
Brandon Kravitz
Last 30d: 57-57-1 (+8.8u)
SF -3+106
2.12u
RoyalsProps
Last 30d: 34-43-2 (-14.7u)
J.Waddle o56.5 Rec Yds-114
1.14u
Frank Ammirante
Last 30d: 99-90-0 (-4.3u)
SF -2.5-120
1u
C.McCaffrey o66.5 Rush Yds-109
1.09u
Gilles Gallant
Last 30d: 22-63-1 (-5.3u)
C.Sutton Anytime TD Scorer Yes+250
0.5u
Nick Giffen
Last 30d: 46-115-0 (+3.2u)
B.Purdy u17.5 Rush Yds-112
0.11u
Take 18.5 at 365 but will track at 17.5 since thats more widely available
B.Purdy u17.5 Rush Yds-113
1.02u
Not sure how i made it only 0.1u earlier lol. Meant to do win 1u. Topping off
Action Pod NFL Picks
Last 30d: 37-98-0 (-11.0u)
K.Black o22.5 Rush Yds-115
1u
@wheatonbrando https://youtu.be/fQFEhKL-r_0?is=XtsrWX8zAPTj-oc0
DEN +3-120
1u
@EvanHAbrams https://youtu.be/3zlHdfn163U?is=HRHNRmeLuDMKMRy5
K.Black 40+ Rushing Yards Yes+306
0.33u
@wheatonbrando https://youtu.be/fQFEhKL-r_0?is=XtsrWX8zAPTj-oc0
K.Black 50+ Rushing Yards Yes+560
0.18u
@wheatonbrando https://youtu.be/fQFEhKL-r_0?is=XtsrWX8zAPTj-oc0
K.Black 60+ Rushing Yards Yes+960
0.1u
@wheatonbrando https://youtu.be/fQFEhKL-r_0?is=XtsrWX8zAPTj-oc0
Mjaybrod
Last 30d: 55-80-1 (-26.1u)
SF u24.5-110
1.82u
NFL POD
Adam Kaufman
Last 30d: 330-306-11 (-13.1u)
Under 13.5 (2Q)-104
0.24u
SF -132 (2Q)
0.19u
SF -122 (1Q)
0.5u
DEN u10.5 (1H)-140
0.18u
Under 23.5 (1H)-120
0.21u
SF o23.5-128
0.2u
SF -2.5-120
1u
SF -136 (1H)
0.25u
Nick Griffith
Last 30d: 54-47-0 (+9.7u)
DEN +3-117
1.17u
Scott Rickenbach
Last 30d: 93-94-2 (-11.6u)
DEN +3-102
1u
John Feltman
Last 30d: 95-58-1 (+20.0u)
Over 48.5-105
0.53u
Sir Lockselot
Last 30d: 14-37-0 (-3.9u)
DEN +145 (Live)
$120.00
Derek Carty
Last 30d: 20-18-0 (+4.9u)
M.Evans u3.5 Recs+114
1u
There may be some value on the receptions prop for Mike Evans. THE BLITZ is projecting him to record 2.87 receptions, and the oddsmakers are implying 4.06. The model believes there is a 68% chance he records fewer than 3.5 receptions. If you can get the under at +114 or better, there is some great value here. This play is good down to at least -146.
Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Kendra Middleton
Last 30d: 15-17-0 (+0.5u)
DEN +2.5+106
0.5u
TAN Pod Touchdown Show
Last 30d: 20-96-6 (-8.9u)
C.Sutton Anytime TD Scorer Yes+240
0.42u
L.Farrell Anytime TD Scorer Yes+1000
0.1u
Kev Mahserejian
Last 30d: 14-18-0 (-1.0u)
DEN +2.5-103
1u
Broncos vs. 49ers Previews & Analysis
Broncos vs. 49ers Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Broncos vs. 49ers Public Betting Percentages
Betting Trends
- 49ers are 5-0 in their last 5 games.
- 49ers are 3-2 in their last 5 games against the spread
- 49ers are 1-0 in their road games against the spread
- The totals have gone OVER in 2 of 49ers' last 5 games
- The totals have gone OVER in 2 of 49ers' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Broncos vs. 49ers Injury Updates

Broncos Injuries
- Tyler BadieRB
Badie is out with thumb
Out
- Pat BryantWR
Bryant is out with ankle
Out

49ers Injuries
- Mike EvansWR
Evans is out with achilles
Out
- Demarcus RobinsonWR
Robinson is out with ankle
Out
- Deebo SamuelWR
Samuel is out with hamstring
Out
- Jake TongesTE
Tonges is out with knee
Out
- De'Zhaun StriblingWR
Stribling is out with ankle
Out
Team Stats
Broncos vs. 49ers Odds Comparison
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Broncos at 49ers Team Totals
MatchupOverUnder | ||
|---|---|---|
Broncos 4-2 | N/A | N/A |
49ers 6-0 | N/A | N/A |




