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Giants vs. Rams Odds & Betting Predictions - September 22, 2026

Giants at Rams

12:15 am • ABC/ESPN

New York Giants

0-0
@

Los Angeles Rams

0-0

Giants at Rams Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Giants
0-0
+8.5
+8.5-110
o47.5-110
+295
Rams
0-0
u47.5
-8.5-110
u47.5-110
-375
location pinTuesday 12:15 a.m.
September 22, 2026
SoFi StadiumInglewood

Giants vs. Rams Props

Prop Projections

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Prop Odds Comparison

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Line Movement Tracker

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Giants vs. Rams Public Betting Percentages

Away Logo

Giants

Public

Home Logo

Rams

100%

Bets%

0%

Money%

NFL Public Betting Right Arrow

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Rams		N/AN/AN/AN/AN/A
Giants		N/AN/AN/AN/AN/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Rams		N/AN/AN/AN/AN/A
Giants		N/AN/AN/AN/AN/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Rams		N/AN/AN/AN/AN/A
Giants		N/AN/AN/AN/AN/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Jan 25th@SEAL 27-31+2.5 LO 45.5SEA +120
Jan 18th@CHIW 20-17-3.5 LU 49.5LA -205
Jan 10th@CARW 34-31-10 LO 45LA -567
Jan 4thARIW 37-20-14.5 WO 49.5LA -1248
Dec 30th@ATLL 24-27-7.5 LO 49ATL -382

Giants vs. Rams Injury Updates

Giants Injuries

  • Malik Nabers
    WR

    Nabers is out with knee

    Out

  • Theo Johnson
    TE

    Johnson is out with illness

    Out

  • Cam Skattebo
    RB

    Skattebo is out with ankle

    Out

Rams Injuries

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    Depth Charts
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    Starter2ND3RD4TH
    QBMatthew StaffordJimmy GaroppoloStetson Bennett
    RBKyren WilliamsBlake CorumJarquez HunterRonnie RiversJordan Waters
    WRTutu AtwellXavier Smith
    TETyler HigbeeColby ParkinsonTerrance FergusonDavis AllenMark Redman
    LTAlaric JacksonD.J. HumphriesAJ Arcuri
    LGSteve AvilaWyatt Bowles
    CColeman SheltonBeaux LimmerDylan McMahon
    RGKevin DotsonJustin Dedich
    RTWarren McClendonDavid Quessenberry
    RDEBraden FiskeDesjuan Johnson
    LCBDarious WilliamsEmmanuel ForbesCam Lampkin
    SSKam CurlJaylen McCollough
    FSKamren KinchensTanner IngleNate Valcarcel
    RCBAhkello WitherspoonCobie DurantDerion Kendrick
    PEthan Evans
    HEthan Evans
    PRXavier Smith
    KRJordan WhittingtonBlake Corum
    LOLBByron Young
    LWRDavante AdamsJordan WhittingtonTru Edwards
    RWRPuka NacuaKonata MumpfieldBrennan Presley
    RILBOmar SpeightsElias Neal
    DTKobie TurnerTyler Davis
    LILBNate LandmanTroy ReederShaun Dolac
    NTPoona FordTy HamiltonBill Norton
    NBQuentin LakeJosh Wallace
    ROLBJared VerseJosaiah StewartNick Hampton

    Giants vs. Rams Odds Comparison

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    Giants at Rams Team Totals

    MatchupOverUnder
    Giants
    0-0
    N/A
    N/A
    Rams
    0-0
    N/A
    N/A